業績｜論文・出版物｜目次｜ALL

Fiber-knob region of adenovirus type 5 vector promotes migration of A549 cells

Kano J., Koizumi N., Terada A., Matsuoka A., Hirai T., Nomura T., Mizuguchi H., Utoguchi N.

BPB Reports, 4, 17-21 (2021)

In vivo gene expression profile of human intestinal epithelial cells: from the viewpoint of drug metabolism and pharmacokinetics

Takayama K., Ito K., Matsui A., Yamashita T., Kawakami K., Hirayama D., Kishimoto W., Nakase H., Mizuguchi H.

Drug Metab. Dispos., 49, 221-232 (2021)

PubMed

アデノウイルスベクターワクチン設計のサイエンス　～COVID-19に対するワクチン開発を中心に～

水口裕之

医学のあゆみ, 279, 999-1004 (2021)

WebSite

ゲノム編集によるヒトiPS細胞モデルの作製技術と医薬品評価への応用

鳥羽由希子、新谷友啓、水口裕之

月刊PHARMSTAGE, 株式会社技術情報協会, 21, 21-27 (2021)

WebSite

ゲノム編集モデルの医薬品評価への応用とその課題

鳥羽由希子, 水口裕之

ゲノム編集技術の産業応用技術〜研究動向、課題とその解決、トラブル対策〜, 株式会社技術情報協会, 339-345 (2021)

WebSite

Tolloid-like 1 negatively regulates hepatic differentiation of human iPS cells through transforming growth factor beta signaling

Kiso A., Toba Y., Tsutsumi S., Deguchi S., Igai K., Koshino S., Tanaka Y., Takayama K., Mizuguchi H.

Hepatol. Commun., 4, 255-267 (2020)

PubMed

Photoactivatable oncolytic adenovirus for optogenetic cancer therapy

Hagihara Y., Sakamoto A., Tokuda T., Yamashita T., Ikemoto S., Kimura A., Haruta M., Sasagawa K., Ohta J., Takayama K., Mizuguchi H.

Cell Death Dis., 11, 570 (2020)

PubMed

Establishment of MDR1-knockout human induced pluripotent stem cell line

Negoro R., Kawai K., Ichikawa M., Deguchi S., Takayama K., Mizuguchi H.

Drug Metab. Pharmacokinet., 35, 288-296 (2020)

PubMed

Oncolytic Virus-Mediated Targeting of the ERK Signaling Pathway Inhibits Invasive Propensity in Human Pancreatic Cancer

Koujima T., Tazawa H., Ieda T., Araki H., Fushimi T., Shoji R., Kuroda S., Kikuchi S., Yoshida R., Umeda Y., Teraishi F., Urata Y., Mizuguchi H., Fujiwara T.

Mol. Ther. Oncolytics, 17, 107-117 (2020)

PubMed

Comparison of commercially available media for hepatic differentiation and hepatocyte maintenance

Toba Y., Deguchi S., Mimura N., Sakamoto A., Harada K., Hirata K., Takayama K., Mizuguchi H.

PLoS One, 15, e0229654 (2020)

PubMed

Immune Modulation by Telomerase-Specific Oncolytic Adenovirus Synergistically Enhances Antitumor Efficacy with Anti-PD1 Antibody

Kanaya N., Kuroda S., Kakiuchi Y., Kumon K., Tsumura T., Hashimoto M., Morihiro T., Kubota T., Aoyama K., Kikuchi S., Nishizaki M., Kagawa S., Tazawa H., Mizuguchi H., Urata Y., Fujiwara T.

Mol. Ther., 28, 794-804 (2020)

PubMed

Development of a Novel Oncolytic Adenovirus Expressing a Short-hairpin RNA Against Cullin 4A

Wakabayashi K., Sakurai F., Ono R., Fujiwara T., Mizuguchi H.

Anticancer Res., 40, 161-168 (2020)

PubMed

Ablation of IL-17A leads to severe colitis in IL-10-deficient mice: implications of myeloid-derived suppressor cells and NO production

Tachibana M., Watanabe N., Koda Y., Oya Y., Kaminuma O., Katayama K., Fan Z., Sakurai F., Kawabata K., Hiroi T., Mizuguchi H.

Int. Immunol., 32, 187-201 (2020)

PubMed

Generation of human induced pluripotent stem cell-derived hepatocyte-like cells for cellular medicine

Deguchi S., Takayama K., Mizuguchi H.

Biol. Pharm. Bull., 43, 608-615 (2020)

PubMed

Aspects of gene therapy products using current genome-editing technology in Japan

Yamaguchi T., Uchida E., Okada T., Ozawa K., Onodera M., Kume A., Shimada T., Takahashi S., Tani K., Nasu Y., Mashimo T., Mizuguchi H., Mitani K., Maki K.

Hum. Gene Ther., 31, 1043-1053 (2020)

PubMed

ヒトiPS細胞由来肝細胞のB型肝炎ウイルス感染評価系への応用

櫻井文教, 水口裕之

ファルマシア, 日本薬学会, 56, 1099-1103 (2020)

J-STAGE

薬物動態評価系としてのヒトiPS細胞由来腸管上皮細胞の可能性

山下智起, 横田純平, 乾達也, 水口裕之

Drug Delivery System, 日本DDS学会, 35, 309-318 (2020)

J-STAGE

CHOPCHOP v3を用いたCRISPR-Cas9の標的配列検索方法

塚本智仁, 酒井英子, 櫻井文教, 水口裕之

Drug Delivery System, 日本DDS学会, 35, 257-259 (2020)

J-STAGE

Establishment of SLC15A1/PEPT1-knockout human induced pluripotent stem cell line for intestinal drug absorption studies

Kawai K., Negoro R., Ichikawa M., Yamashita T., Deguchi S., Harada K., Hirata K., Takayama K., Mizuguchi H.

Mol. Ther. Methods Clin. Dev., 17, 49-57 (2019)

PubMed

Efficient generation of adenovirus vectors carrying the Clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR associated proteins (Cas)12a system by suppressing Cas12a expression in packaging cells

Tsukamoto T., Sakai E., Nishimae F., Sakurai F., Mizuguchi H.

J. Biotech., 304, 1-9 (2019)

PubMed

目次に戻る

大阪大学大学院薬学研究科分子生物学分野

Laboratory of Biochemistry and Molecular Biology

Graduate School of Pharmaceutical Sciences, Osaka University

業績｜論文・出版物｜目次｜ALL