業績｜論文・出版物｜目次｜ALL

Dendritic cells transduced with gp100 gene by RGD fiber-mutant adenovirus vectors are highly efficacious in generating anti-B16BL6 melanoma immunity in mice

Okada N., Masunaga Y., Okada Y., Mizuguchi H., Iiyama S., Mori N., Sasaki A., Nakagawa S., Mayumi T., Hayakawa T., Fujita T., Yamamoto A.

Gene Ther., 10, 1891-1902 (2003)

PubMed

Vanadate enhances leptin-induced activation of JAK/STAT pathway in CHO cells

Kita A., Uotani S., Kuwahara H., Takahashi R., Oshima K., Yamasaki H., Mizuguchi H., Hayakawa T., Nagayama Y., Yamaguchi Y., Eguchi K.

Biochem. Biophys. Res. Commun., 302, 805-809 (2003)

PubMed

Postinfarction treatment with an adenoviral vector expressing hepatocyte growth factor relieves chronic left ventricular remodeling and dysfunction in mice

Li Y., Takemura G., Kosai K.I., Yuge K., Nagano S., Esaki M., Goto K., Takahashi T., Hayakawa K., Koda M., Kawase Y., Maruyama R., Okada H., Minatoguchi S., Mizuguchi H., Fujiwara T., Fujiwara H.

Circulation, 107, 2499-2506 (2003)

PubMed

Thyroid cancer immuno-therapy with retroviral and adenoviral vectors expressing granulocyte macrophage colony stimulating factor and interleukin-12 in a rat model

Tanaka K., Towata S., Nakao K., Mizuguchi H., Hayakawa T., Niwa M., Ishii N., Nagayama Y.

Clin. Endocrinol., 59, 734-742 (2003)

PubMed

Prevention of autoantibody-mediated Graves'-like hyperthyroidism in mice with IL-4, a Th2 cytokine

Nagayama Y, Mizuguchi H., Hayakawa T., Niwa M., McLachlan SM., Rapoport B.

J. Immunol., 170, 3522-3527 (2003)

PubMed

Enhanced antitumor effect of combined replicative adenovirus and nonreplicative adenovirus expressing interleukin-12 in an immunocompetent mouse model

Nagayama Y., Nakao, K., Mizuguchi H., Hayakawa T., Niwa M.

Gene Ther., 10, 1400-1403 (2003)

PubMed

Role of H1-calponin in pancreatic AR42J cell differentiation into insulin-producing cells

Morioka T., Koyama H., Yamamura H., Tanaka S., Fujimoto, S., Emoto M., Mizuguchi H., Hayakawa T., Kojima I., Takahashi K., Nishizawa Y.

Diabetes, 52, 760-766 (2003)

PubMed

A novel T7 system utilizing mRNA coding for T7 RNA polymerase

Nakano R., Nakagawa T., Imazu S., Katayama K., Mizuguchi H., Hayakawa T., Tsutsumi Y., Nakagawa S., Mayumi T.

Biochem. Biophys. Res. Commun., 301, 974-978 (2003)

PubMed

Gene transduction efficiency and maturation status in mouse bone marrow-derived dendritic cells infected with conventional or RGD fiber-mutant adenovirus vectors

Okada N., Masunaga Y., Okada Y., Iiyama S., Tsuda T., Matsubara A., Mori N., Mizuguchi H., Hayakawa T., Fujita T., Yamamoto A.

Cancer Gene Ther., 10, 421-431 (2003)

PubMed

A novel PPAR gamma gene therapy to control inflammation associated with inflammatory bowel disease in a murine model

Katayama K., Wada K., Nakajima A., Yoshida S., Mizuguchi H., Hayakawa T., Nakagawa S., Kadowaki T, Nagai R., Kamisaki Y, Blumberg RS., Mayumi T.

Gastroenterology, 124, 1315-1324 (2003)

PubMed

An investigation of adverse effects caused by the injection of high-dose TNFα-expressing adenovirus vector into established murine melanoma

Okada Y., Okada N., Mizuguchi H., Hayakawa T., Mayumi T., Mizuno N.

Gene Ther., 10, 700-705 (2003)

PubMed

In vivo expression of B:9-23 peptide/I-Ag7 complex may abrogate the inhibition of diabetes induced by RGD-fiber-mutant adenovirus in NOD mice

Abiru N., Sun F., Kawasaki E., Yamasaki H., Oshima K., Nagayama Y., Mizuguchi H., Hayakawa T., Miao D., Liu E., Eisenbarth G.S., Eguchi K.

Annals N.Y. Acad. Sci., 1005, 218-221 (2003)

PubMed

Long-term hematopoietic stem cells require stromal cell-derived factor-1 for colonizing bone marrow during ontogeny

Ara T., Tokoyoda K., Sugiyama T., Egawa T., Kawabata K., Nagasawa T.

Immunity, 19, 257-267 (2003)

PubMed

A role of CXC chemokine ligand 12/stromal cell-derived factor-1/pre-B cell growth stimulating factor and its receptor CXCR4 in fetal and adult T cell development in vivo

Ara T., Itoi M., Kawabata K., Egawa T., Tokoyoda K., Sugiyama T., Fujii N., Amagai T., Nagasawa T.

J. Immunol., 170, 4649-4655 (2003)

PubMed

Therapeutic effect of intravenous delivery of lipoplexes containing the interferon-beta gene and poly I: poly C in a murine lung metastasis model

Sakurai F., Terada T., Maruyama M., Yamashita F., Takakura Y., and Hashida M.

Cancer Gene Ther., 10, 661-668 (2003)

PubMed

次世代遺伝子治療薬の開発基盤研究

水口裕之

薬学雑誌, 日本薬学会, 123, 761-771 (2003)

J-STAGE

アデノウイルスベクター：最近の進歩

水口裕之, 早川堯夫

分子細胞治療, 2, 200-207 (2003)

遺伝子機能解析のための遺伝子導入ベクター -ウイルスベクターを中心として-

水口裕之, 早川堯夫

蛋白質核酸酵素, 48, 1653-1662 (2003)

21世紀のDDS：発展を担う立場から

橋田充, 水口裕之, 山下富義, 横山昌幸, 原島秀吉, 米谷芳枝, 松村保広, 岡田純一, 五十嵐理慧

Drug Delivery System, 日本DDS学会, 18, 7-20 (2003)

CiNii

CAR- orαv integrin-binding ablated adenovirus vectors, but not fiber-modified vectors containing RGD peptide, do not change the systemic gene transfer properties in mice

Mizuguchi H., Koizumi N., Hosono T., Ishii-Watabe A., Uchida E., Utoguchi N., Watanabe Y., Hayakawa T.

Gene Ther., 9, 769-776 (2002)

PubMed

目次に戻る

大阪大学大学院薬学研究科分子生物学分野

Laboratory of Biochemistry and Molecular Biology

Graduate School of Pharmaceutical Sciences, Osaka University

業績｜論文・出版物｜目次｜ALL