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業績|論文・出版物|目次|ALL
 

Simultaneous imaging of initiator/effector caspase activity and mitochondrial membrane potential during cell death in living HeLa cells

Kawai H., Suzuki T., Kobayashi T., Mizuguchi H., Hayakawa T., Kawanishi T.

Biochim. Biophys. Acta, 1693, 101-110 (2004)

Neutralizing antibody evasion ability of adenovirus vector induced by the bioconjugation of methoxypolyethylene glycol succinimidyl propionate (MPEG-SPA)

Eto Y., Gao J-Q., Sekiguchi F., Kurachi S., Katayama K., Mizuguchi H., Hayakawa T., Tsutsumi Y., Mayumi T., Nakagawa S.

Biol. Pharm. Bull., 27, 936-938 (2004)

Antibody-targeted cell fusion

Nakamura T., Peng K-W., Vongpunsawad S., Harvey M., Mizuguchi H., Hayakawa T., Cattaneo R., Russell S.J.

Nat. Biotech., 22, 331-336 (2004)

Optimization of antitumor efficacy and safety of in vivo cytokine gene therapy using RGD fiber-mutant adenovirus vector for preexisting murine melanoma

Okada Y., Okada N., Mizuguchi H., Takahashi K., Hayakawa T., Mayumi T., Mizuno N.

Biochim. Biophys. Acta, 1670, 172-180 (2004)

Anti-tumor activity of chemokine is affected by both kinds of tumors and the activation state of the host's immune system: implications for chemokine-based cancer immunotherapy

Okada N., Gao J-Q., Sasaki A., Niwa M., Okada Y., Nakayama T., Yoshie O., Mizuguchi H., Hayakawa T., Fujita T., Yamamoto A., Tsutsumi Y., Mayumi T., Nakagawa S.

Biochem. Biophys. Res. Commun., 317, 68-76 (2004)

Overexpression of constitutively activated glutamate dehydrogenase induces insulin secretion through enhanced glutamate oxidation

Anno T., Uehara S., Katagiri H., Ohta Y., Ueda K., Mizuguchi H., Moriyama Y., Oka Y., Tanizawa Y.

Am. J. Physiol., 286, E280-285 (2004)

Tumor-suppressive activities by chemokines introduced into OV-HM cells using fiber-mutant adenovirus vectors

Gao J-Q, Alexandre L.S., Tsuda Y., Katayama K., Eto Y., Sekiguchi F., Mizuguchi H., Hayakawa T., Nakayama T., Yoshie O., Tsutsumi Y., Mayumi T., Nakagawa S.

Pharmazie, 59, 238-239 (2004)

RNA interfering approach for clarifying PPARγ pathway using lentiviral vector expressing short hairpin RNA

Katayama K., Wada K., Miyoshi H., Ohashi K., Tachibana M., Furuki R., Mizuguchi H., Hayakawa T., Nakajima A., Kadowaki T., Tsutsumi Y., Nakagawa1 S., Kamisaki Y., Mayumi T.

FEBS Lett., 560, 178-182 (2004)

Dominant negative mutant of c-Jun gene transfer: a novel therapeutic strategy for colorectal cancer

Suto R., Tominaga K., Mizuguchi H., Sasaki E., Higuchi K., Kim S., Iwao H., Arakawa T.

Gene Ther., 11, 187-193 (2004)

アデノウイルスベクター

水口裕之, 早川堯夫

Mebio, メジカルビュー社, 21, 8-16 (2004)

Reduction of natural adenovirus tropism to mouse liver by fiber-shaft exchange in combination with both CAR- and αv integrin-binding ablation

Koizumi N., Mizuguchi H., Sakurai F., Yamaguchi T., Watanabe Y., Hayakawa T.

J. Virol., 77, 13062-13072 (2003)

Detection of replication-competent adenoviruses spiked into recombinant adenovirus vector products by infectivity PCR

Ishi-Watabe A., Uchida E., Iwata A., Nagata R., Satoh K., Fan K., Murata M., Mizuguchi H., Kawasaki N., Kawanishi T., Yamaguchi T., Hayakawa T.

Mol. Ther., 8, 1009-1016 (2003)

Characterization of in vitro and in vivo gene transfer properties of adenovirus serotype 35 vector

Sakurai F., Mizuguchi H., Yamaguchi T., Hayakawa T.

Mol. Ther., 8, 813-821 (2003)

Tight positive regulation of transgene expression by a single adenovirus vector containing the rtTA and tTS expression cassettes in separate genome regions

Mizuguchi H., Xu Z.L., Sakurai F., Mayumi T., Hayakawa T.

Hum. Gene Ther., 14, 1265-1277 (2003)

Antitumor effect by interleukin-11 receptor alpha-locus chemokine/CCL27, introduced into tumor cells through a recombinant adenovirus vector

Gao J-Q, Tsuda Y., Katayama K., Nakayama T., Hatanaka Y., Tani Y., Mizuguchi H., Hayakawa T., Yoshie O., Tsutsumi Y., Mayumi T., Nakagawa S.

Cancer Res., 63, 4420-4425 (2003)

Efficient gene transfer into human CD34+ cells by an adenovirus type 35 vector

Sakurai F., Mizuguchi H., Hayakawa T.

Gene Ther., 10, 1041-1048 (2003)

Generation of fiber-modified adenovirus vectors containing heterologous peptides in both the HI loop and C terminus of the fiber knob

Koizumi N., Mizuguchi H., Utoguchi N., Watanabe Y., Hayakawa T.

J. Gene Med., 5, 267-276 (2003)

Regulated gene expression from adenovirus vectors: a systematic comparison of various inducible systems

Xu Z.L., Mizuguchi H., Mayumi T., Hayakawa T.

Gene, 309, 145-151 (2003)

Woodchuck hepatitis virus post-transcriptional regulation element enhances transgene expression from adenovirus vectors

Xu Z.L., Mizuguchi H., Mayumi T., Hayakawa T.

Biochim. Biophys. Acta, 1621, 266-271 (2003)

A soluble CAR-SCF fusion protein improves adenoviral vector-mediated gene transfer to c-Kit-positive hematopoietic cells

Itoh A., Okada T., Mizuguchi H., Hayakawa T., Mizukami H., Kume A., Takatoku M., Komatsu A., Hanazono Y., Ozawa K.

J. Gene Med., 5, 929-940 (2003)

大阪大学大学院 薬学研究科 分子生物学分野 

〒565-0871 大阪府吹田市山田丘1-6 大阪大学 大学院薬学研究科・薬学部 1号館 4階

TEL: 06-6879-8185 FAX: 06-6879-8187

Copyright© Laboratory of Biochemistry and Molecular Biology, Graduate School and School of Pharmaceutical Sciences, Osaka University

directed by Prof. Hiroyuki Mizuguchi

  • 分子生物学分野 | 阪大 | 薬学 | 生化 twitter
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