業績｜論文・出版物｜目次｜ALL

Recent Advance of Development of Viral and Non-viral Vectors for Gene Therapy

Mizuguchi H.

Yakugaku Zasshi, 126, 1011 (2006)

PubMed

Characterization of adenovirus serotype 35 vectors using genetically modified animals and nonhuman primates

Sakurai F., Kawabata K., Mizuguchi H.

Yakugaku Zasshi, 126, 1013-1019 (2006)

PubMed

Development of non-viral vector based on the quantitative comparison of intracellular trafficking with viral vector

Akita H., Hama S., Mizuguchi H., Harashima H.

Yakugaku Zasshi, 126, 1047-1057 (2006)

PubMed

新しいアデノウイルスベクターの開発

櫻井文教, 水口裕之

バイオサイエンスとインダストリー, バイオインダストリー協会, 64, 11-16 (2006)

CiNii

創薬・創剤人

櫻井文教, 川端健二

Pharm Tech Japan, 22, 18-19 (2006)

WebSite

Efficient gene transfer into mouse embryonic stem cells with adenovirus vectors

Kawabata K., Sakurai F., Yamaguchi T., Hayakawa T., Mizuguchi H.

Mol. Ther., 12, 547-554 (2005)

PubMed

Optimization of adenovirus serotype 35 vectors for efficient transduction in human hematopoietic progenitors: comparison of promoter activities

Sakurai F., Kawabata K., Yamaguchi T., Hayakawa T., Mizuguchi H.

Gene Ther., 12, 1424-1433 (2005)

PubMed

Fiber-modified adenovirus vectors mediate efficient gene transfer into undifferentiated and adipogenic-differentiated human mesenchymal stem cell

Mizuguchi H., Sasaki T., Kawabata K., Sakurai F., Hayakawa T.

Biochem. Biophys. Res. Commun., 332, 1101-1106 (2005)

PubMed

A trial of somatic gene targeting in vivo with an adenovirus vector

Ino A., Naito Y., Mizuguchi H., Handa N., Hayakawa T., Kobayashi I.

Genet. Vaccines Ther., 3, 8 (2005)

PubMed

Efficient regulation of gene expression using self-contained fiber-modified adenovirus vectors containing the tet-off system

Mizuguchi H., Xu Z-L., Sakurai F., Kawabata K., Yamaguchi T., Hayakawa T.

J. Control. Release, 110, 202-211 (2005)

PubMed

Prime-boost vaccination with plasmid DNA and a chimeric adenovirus type 5 vector with type 35 fiber induces protective immunity against HIV

Xin K-Q., Jounai N., Someya K., Honma K., Mizuguchi H., Naganawa S., Kitamura K., Hayakawa T., Saha S., Takeshita F., Okuda K., Honda M., Klinman D.M., Okuda K.

Gene Ther., 12, 1769-1777 (2005)

PubMed

Role of C-terminal regions of the C-terminal fragment of Clostridium perfringens enterotoxin in its interaction with claudin-4

Takahashi A., Kondoh M., Masuyama A., Fujii M., Mizuguchi H., Horiguchi Y., Watanabe Y.

J. Control. Release, 108, 56-62 (2005)

PubMed

Role of N-terminal amino acids in the absorption-enhancing effects of the C-terminal fragment of Clostridium Perfringens enterotoxin

Masuyama A., Kondoh M., Seguchi H., Takahashi A., Harada M., Fujii M., Mizuguchi H., Horiguchi Y., Watanabe Y.

J. Pharmacol. Exp. Ther., 314, 789-795 (2005)

PubMed

Anti-tumor responses induced by chemokine CCL19 transfected into an ovarian carcinoma model via fiber-mutant adenovirus vector

Gao J-Q, Sugita T., Kanagawa N., Iida K., Okada N., Mizuguchi H., Nakayama T., Yoshie O., Tsutsumi Y., Mayumi T., Nakagawa S.

Biol. Pharm. Bull., 28, 1066-1070 (2005)

PubMed

Transcriptional targeting of RGD fiber-mutant adenovirus vectors can improve the safety of suicide gene therapy for murine melanoma

Okada Y., Okada N., Mizuguchi H., Hayakawa T., Nakagawa S., Mayumi T.

Cancer Gene Ther., 12, 608-616 (2005)

PubMed

Comparison of transgene expression mediated by several fiber-modified adenovirus vectors in trophoblast cells

Koizumi, N., Kondoh, M., Mizuguchi H., Nakanishi, T., Masuyama, A., Ida, F., Fujii, M., Hayakawa, T., Nakashima, E., Tanaka, K., Watanabe, Y.

Placenta, 26, 729-734 (2005)

PubMed

PEGylated adenovirus vectors containing RGD peptides on the tip of PEG show high transduction efficiency and antibody evasion ability

Eto Y., Gao J-Q., Sekiguchi F., Kurachi S., Katayama K., Mizuguchi H., Hayakawa T., Maeda, M., Kawasaki K., Tsutsumi Y., Mayumi T., Nakagawa S.

J. Gene Med., 7, 604-612 (2005)

PubMed

Enhanced oncolysis by a tropism-modified telomerase-specific replication-selective adenoviral agent OBP-405 ('Telomelysin-RGD')

Taki M., Kagawa S., Nishizaki M., Mizuguchi H., Hayakawa T., Kyo S., Nagai K., Urata Y., Tanaka N., Fujiwara T.

Oncogene, 24, 3130-3140 (2005)

PubMed

Design and synthesis of a peptide-PEG transporter tool for carrying adenovirus vector into cells

Maeda M., Kida S., Hojo K., Eto Y., Gao J-Q, Kurachi S., Sekiguchi F., Mizuguchi H., Hayakawa T., Mayumi T., Nakagawa S., Kawasaki K.

Bioorg. Med. Chem. Lett., 15, 621-624 (2005)

PubMed

A single intratumoral injection of a fiber-mutant adenoviral vector encoding interleukin 12 induces remarkable anti-tumor and anti-metastatic activity in mice with Meth-A fibrosarcoma

Gao J-Q, Sugita T., Kanagawa N., Iida K., Eto Y., Motomura Y., Mizuguchi H., Tsutsumi Y., Hayakawa T., Mayumi T., Nakagawa S.

Biochem. Biophys. Res. Commun., 328, 1043-1050 (2005)

PubMed

目次に戻る

大阪大学大学院薬学研究科分子生物学分野

Laboratory of Biochemistry and Molecular Biology

Graduate School of Pharmaceutical Sciences, Osaka University

業績｜論文・出版物｜目次｜ALL