業績｜論文・出版物｜目次｜ALL

Adenovirus type 5 with modified hexons induces robust transgene-specific immune responses in mice with pre-existing immunity against adenovirus type 5

Abe S., Okuda K., Ura T., Kondo A., Yoshida A., Yoshizaki S., Mizuguchi H., Klinman D., Shimada M.

J. Gene Med., 11, 570-579 (2009)

PubMed

Suppressive effects of sugar-modified cationic liposome/NF-κB decoy complexes on adenovirus vector-induced innate immune responses

Huang H., Sakurai F., Higuchi Y., Kawakami S., Hashida M., Kawabata K., Hayakawa T., Mizuguchi H.

J. Control. Release, 133, 139-145 (2009)

PubMed

NK cells are migrated and indispensable in the anti-tumor activity induced by CCL27 gene therapy

Gao J-Q., Tsuda Y., Han M., Xu D-H., Kanagawa N., Hatanaka Y., Tani Y., Mizuguchi H., Tsutsumi Y., Mayumi T., Okada N., Nakagawa S.

Cancer Immunol. Immunother., 58, 291-299 (2009)

PubMed

Effect of therapeutic immunization using Ad5/35 and MVA vectors on SIV-infection of rhesus monkeys undergoing anti-retroviral therapy

Shimada M, Wang H-B., Ino A., Xu X-P., Yoshida A., Shinoda K., Ura T., Mizuguchi H., Klinman D., Luo J-L., Bai H., Okuda K.

Gene Ther., 16, 218-228 (2009)

PubMed

改良型アデノウイルスベクター開発の最前線

水口裕之

脳２１, 金芳堂, 12, 123-131 (2009)

WebSite

アデノウイルスベクターの作製・増幅・精製法

水口裕之

脳２１, 金芳堂, 12, 246-251 (2009)

WebSite

iPS細胞を活用した安全性・有効性評価系の構築

古江－楠田美保, 山田弘, 水口裕之

iPS細胞の産業的応用技術, シーエムシー出版, 218～224 (2009)

WebSite

アデノウイルスベクターのDDS

水口裕之, 櫻井文教, 川端健二

Pharm Tech Japan, 25, 2618-2624 (2009)

ゲノム解析と遺伝子DDSの設計・評価

水口裕之

Pharm Tech Japan, 25(13) (2009)

WebSite

組換えウイルスキャリア－遺伝子治療・ワクチン応用への新展開－

水口裕之

Drug Delivery System, 日本DDS学会, 24, 569 (2009)

CiNii

遺伝子組換えウイルスの安全性向上に向けた遺伝子改変～microRNAによる遺伝子発現制御システムを搭載した組換えウイルスの開発～

櫻井文教, 川端健二, 水口裕之

Drug Delivery System, 日本DDS学会, 24, 572-581 (2009)

J-STAGE

miR-122a-regulated expression of a suicide gene prevents hepatotoxicity without altering antitumor effects in suicide gene therapy

Suzuki T., Sakurai F., Nakamura S-I., Kouyama E., Kawabata K., kondoh M., Yagi K., Mizuguchi H.

Mol. Ther., 16, 1719-1726 (2008)

PubMed

Adenoviral expression of suppressor of cytokine signaling-1 reduces adenovirus vector-induced innate immune response

Sakurai H., Tashiro K., Kawabata K., Yamaguchi T., Sakurai F., Nakagawa S., Mizuguchi H.

J. Immunol., 180, 4931-4938 (2008)

PubMed

Transduction properties of adenovirus serotype 35 vectors after intravenous administration into nonhuman primates

Sakurai F., Nakamura S-I., Akitomo K., Shibata H., Terao K., Kawabata K., Hayakawa T., Mizuguchi H.

Mol. Ther., 16, 726-733 (2008)

PubMed

Efficient adenovirus vector-mediated PPAR gamma gene transfer into mouse embryoid bodies promotes adipocyte differentiation, J

Tashiro K., Kawabata K., Sakurai H., Kurachi S., Sakurai F., Yamanishi K., Mizuguchi H.

Gene Med., 10, 498-507 (2008)

PubMed

Efficient gene delivery in human and rodent mast cells using adenovirus vectors

Nakashima K., Sakurai F., Kawabata K., Mizuguchi H.

J. Control. Release, 129, 215-222 (2008)

PubMed

Innate immune response induced by gene delivery vectors

Sakurai H., Kawabata K., Sakurai F., Nakagawa S., Mizuguchi H.

Int. J. Pharm., 354, 9-15 (2008)

PubMed

Modification of pIX or hexon based on fiberless Ad vectors is not effective for targeted Ad vectors

Kurachi S., Koizumi N., Tashiro K., Sakurai H., Sakurai F., Kawabata K., Nakagawa S., Mizuguchi H.

J. Control. Release, 127, 88-95 (2008)

PubMed

Engineering of highly immunogenic long-lived DC vaccines by antiapoptotic protein gene transfer to enhance cancer vaccine potency

Yoshikawa T., Niwa T., Okada N., Mizuguchi H., Nakagawa S.

Gene Ther., 15, 1321-1329 (2008)

PubMed

Combination of two fiber-mutant adenovirus vectors, one encoding the chemokine FKN and another encoding cytokine interleukin 12, elicits notably enhanced anti-tumor responses

Gao J-Q., Kanagawa N., Xu D-H., Han M., Sugita T., Hatanaka Y., Tani Y., Mizuguchi H., Tsutsumi Y., Mayumi T., Okada N., Nakagawa S.

Cancer Immunol. Immunother., 57, 1657-64 (2008)

PubMed

目次に戻る

大阪大学大学院薬学研究科分子生物学分野

Laboratory of Biochemistry and Molecular Biology

Graduate School of Pharmaceutical Sciences, Osaka University

業績｜論文・出版物｜目次｜ALL