業績｜論文・出版物｜目次｜ALL

Endodermal and hepatic differentiation from human embryonic stem cells and human induced pluripotent stem cells

Kawabata K., Takayama K., Nagamoto Y., Saldon M.S., Higuchi M., Mizuguchi H.

J. Stem Cell Res. Ther., S10 (2012)

PubMed

マイクロRNAを利用してウイルス遺伝子の非特異的な発現を抑制可能な新規アデノウイルスベクターの開発

清水かほり, 櫻井文教, 立花雅史, 水口裕之

薬学雑誌, 日本薬学会, 132, 1407-1412 (2012)

J-STAGE

ヒトiPS細胞から肝細胞への分化誘導の現状と創薬応用

水口裕之, 高山和雄, 長基康人, 川端健二

医薬品医療機器レギュラトリーサイエンス, 医薬品医療機器レギュラトリーサイエンス財団, 43, 982-987 (2012)

WebSite

ヒトiPS細胞の再生医療及び創薬研究への応用の現状と展望

早川堯夫, 水口裕之

Brain and Nerve, 64, 47-57 (2012)

WebSite

ウイルスベクターと遺伝子治療

水口裕之, 櫻井文教

新編ウイルスの今日的意味, 医薬ジャーナル社, 101-108 (2012)

WebSite

多能性幹細胞から肝細胞への分化誘導

高山和雄, 川端健二, 水口裕之

再生医療業書, 朝倉書店, 110-116 (2012)

iPS細胞研究の道しるべ　遺伝子治療研究の貢献と教訓

水口裕之

ファルマシア, 日本薬学会, 48, 827 (2012)

J-STAGE

microRNAによる遺伝子発現制御システムを搭載した遺伝子発現ベクター

櫻井文教, 水口裕之

ドラッグデリバリーシステムの新展開II―核酸医薬・抗体医薬・ワクチン医療を支えるDDS技術―, シーエムシー出版, 278, 47-53 (2012)

WebSite

Efficient generation of hepatoblastsfrom human ES cells and iPS cells by transient overexpression of homeobox gene HEX

Inamura M., Kawabata K., Takayama K., Tashiro K., Sakurai F., Katayama K., Toyoda M., Akutsu H., Miyagawa Y.,Okita H., Kiyokawa N., Umezawa A., Hayakawa T., Furue MK., Mizuguchi H.

Mol. Ther., 19, 400-407 (2011)

PubMed

Efficient and directive generation of two distinct endoderm lineages from human ES and iPS cells by differentiation stage-specific SOX17 transduction

Takayama K., Inamura M., Kawabata K., Tashiro K., Katayama K., Hayakawa T., Furue MK., Mizuguchi H.

PLoS One, 6, e21780 (2011)

PubMed

Enhanced safety profiles of the telomerase-specific replication-competent adenovirus by incorporation of normal cell-specific microRNA-targeted sequences

Sugio K., Sakurai F., Katayama K., Matsui H., Kawabata K., Kawase A., Iwaki M., Hayakawa T., Fujiwara T., Mizuguchi H.

Clin. Cancer Res., 17, 2807-2818 (2011)

PubMed

Hexon-specific PEGylated adenovirus vectors utilizing avidin-biotin interaction

Suzuki-Kouyama E., Katayama K., Sakurai F., Yamaguchi T., Kurachi S., Kawabata K., Nakagawa S., Mizuguchi H.

Biomaterials, 32, 1724-1730 (2011)

PubMed

Enhanced transduction efficiency of fiber-substituted adenovirus vectors by the incorporation of RGD peptides in two distinct regions of the adenovirus serotype 35 fiber knob

Matsui H., Sakurai F., Katayama K., Kurachi S., Tashiro K., Sugio K., Kawabata K., Mizuguchi H.

Virus Res., 155, 48-54 (2011)

PubMed

Development of a recombinant adenovirus vector production system free of replication-competent adenovirus by utilizing a packaging size limit of the viral genome

Suzuki T., Sasaki T., Yano K., Sakurai F., Kawabata K., Kondoh M., Hayakawa T., Yagi K., Mizuguchi H.

Virus Res., 158, 154-160 (2011)

PubMed

Use of human hepatocyte-like cells derived from induced pluripotent stem cells as a model for hepatocytes in hepatitis C virus infection

Yoshida T.#, Takayama K.#, Kondoh M.*, Sakurai F., Tani H., Sakamoto N., Matsuura Y., Mizuguchi H*., Yagi K*. #These authors equally contributed to this work. *Co-corresponding author.

Biochem. Biophys. Res. Commun., 416, 119-124 (2011)

PubMed

An effective gene-knockdown using multiple shRNA-expressing adenovirus vectors

Motegi Y., Katayama K., Sakurai F., Kato T., Yamaguchi T., Matsui H., Takahashi M., Kawabata K., Mizuguchi H.

J. Control. Release, 153, 149-153 (2011)

PubMed

Quantitative analysis of the leaky expression of adenovirus genes in cells transduced with a replication-incompetent adenovirus vector

Shimizu K., Sakurai F., Machitani M., Katayama K., Mizuguchi H.

Mol. Pharmaceutics, 8, 1430-1435 (2011)

PubMed

Development of an adenovirus vector lacking the expression of virus-associated RNAs

Machitani M., Katayama K., Sakurai F., Matsui H., Yamaguchi T., Suzuki T., Miyoshi H., Kawabata K., Mizuguchi H.

J. Control. Release, 154, 285-289 (2011)

PubMed

Enhanced in vivo gene transfer into the placenta using RGD fiber-mutant adenovirus vector

Katayama K., Furuki R., Yokoyama H., Kaneko M., Tachibana M., Yoshida I., Nagase H., Tanaka K., Sakurai F., Mizuguchi H., Nakagawa S., Nakanishi T.

Biomaterials, 32, 4185-4193 (2011)

PubMed

Overexpression of SOCS3 exhibits preclinical antitumor activity against malignant pleural mesothelioma

Iwahori K., Serada S., Fujimoto M., Nomura S., Osaki T., Lee C.M., Mizuguchi H., Takahashi T., Ripley B., Okumura M., Kawase I., Kishimoto T., Naka T.

Int. J. Cancer, 129, 993-1005 (2011)

PubMed

目次に戻る

大阪大学大学院薬学研究科分子生物学分野

Laboratory of Biochemistry and Molecular Biology

Graduate School of Pharmaceutical Sciences, Osaka University

業績｜論文・出版物｜目次｜ALL