業績｜論文・出版物｜目次｜ALL

Efficient Adenovirus gene transfer methods in human colonic Caco-2 epithelial cells using capric acid

Koizumi N., Yamagishi Y., Hirai T., Fujii M., Mizuguchi H., Watanabe Y.

Biol. Pharm. Bull., 38, 1240-1244 (2015)

Expression of coxsackievirus and adenovirus receptor separates hematopoietic and cardiac progenitor cells in Flk1-expressing mesoderm

Tashiro K., Hirata N., Okada A., Yamaguchi T., Takayama K., Mizuguchi H., Kawabata K.

Stem Cells Transl. Med., 4, 424-436 (2015)

PubMed

Activity levels of cathepsins B and L in tumor cells are a biomarker for efficacy of reovirus-mediated tumor cell killing

Terasawa Y., Hotani T., Katayama Y., Tachibana M., Mizuguchi H., Sakurai F.

Cancer Gene Ther., 22, 188-97 (2015)

PubMed

Quantitative analysis of virus-associated RNAI expression following transduction with a replication-incompetent adenovirus vector in vitro and in vivo

Wakabayashi K., Machitani M., Shimizu K., Tachibana M., Sakurai F., Mizuguchi H.

J. Mol. Genet. Med., 9, 169 (2015)

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Generation of brain microvascular endothelial-like cells from human induced pluripotent stem cells by co-culture with C6 glioma cells

Minami H., Tashiro K., Okada A., Hirata N., Yamaguchi T., Takayama K., Mizuguchi H., Kawabata K.

PLoS One, 10, e0128890 (2015)

PubMed

Evaluation of transduction properties of an adenovirus vector in neonatal mice

Iizuka S., Sakurai F., Shimizu K., Ohashi K., Nakamura S-I., Tachibana M., Mizuguchi H.

BioMed Res. Int., 685374 (2015)

PubMed

Reovirus double-stranded RNA genomes and polyI:C induce down-regulation of hypoxia-inducible factor-alpha

Hotani T., Tachibana M., Mizuguchi H., Sakurai F.

Biochem. Biophys. Res. Commun., 460, 1041-1046 (2015)

PubMed

Efficient engraftment of human iPS cell-derived hepatocyte-like cells in uPA/SCID mice by overexpression of FNK, a Bcl-xLmutant gene

Nagamoto Y., Takayama K., Tashiro K., Tateno C., Sakurai F., Tachibana M., Kawabata K., Ikeda K., Tanaka Y., Mizuguchi H.

Cell Transplant., 24, 1127-1138 (2015)

PubMed

Proteolytic disassembly of viral outer capsid proteins is crucial for reovirus-mediated type-I interferon induction in both reovirus-susceptible and reovirus-refractory tumor cells

Katayama Y., Terasawa Y., Tachibana M., Mizuguchi H., Sakurai F.

BioMed Res. Int., 468457 (2015)

PubMed

ヒトiPS細胞から肝細胞への高効率分化誘導法の開発とその実用化に関する研究

水口裕之

バイオサイエンスとインダストリー, バイオインダストリー協会, 73, 104-109 (2015)

CiNii

ヒトiPS細胞由来肝細胞の創薬研究・非臨床試験への応用を目指して

高山和雄, 水口裕之

薬剤学, 75, 369-373 (2015)

J-STAGE

Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes

Takayama K., Morisaki Y., Kuno S., Nagamoto Y., Harada K., Furukawa N., Ohtaka M., Nishimura K., Imagawa K., Sakurai F., Tachibana M., Sumazaki R., Noguchi E., Nakanishi M., Hirata K., Kawabata K., Mizuguchi H.

Proc. Natl. Acad. Sci. USA, 111, 16772-16777 (2014)

PubMed

Protective mucosal immunity mediated by epithelial CD1d and IL-10

Olszak T., Neves J., Dowds M., Baker K.K., Glickman J., Davidson N., Lin C-Y., Jobin C., Brand S., Sotlar K., Wada K., Katayama K., Nakajima A., Mizuguchi H., Kawasaki K., Nagata K., Müller W., Snapper S., Schreiber S., Kaser A., Zeissig S., Blumberg RS.

Nature, 509, 497-502 (2014)

PubMed

The Early Activation of CD8(+) T Cells is dependent on type I IFN Ssignaling following intramuscular vaccination of adenovirus vector

Hemmi M.#, Tachibana M.#, Tsuzuki S., Shoji M., Sakurai F., Kawabata K., Kobiyama K., Ishii K.J., Akira S., Mizuguchi H. #These authors equally contributed to this work.

BioMed Res. Int., 158128 (2014)

PubMed

CCAAT/enhancer binding protein-mediated regulation of TGFβ receptor 2 expression determine the hepatoblast fate decision

Takayama K., Kawabata K., Nagamoto Y., Inamura M., Ohashi K., Okuno H., Yamaguchi T., Tashiro K., Sakurai F., Hayakawa T., Okano T., Furue MK., Mizuguchi H.

Development, 141, 91-100 (2014)

PubMed

Development of mice exhibiting hepatic microsomal activity of human CYP3A4 comparable to that in human liver microsomes by intravenous administration of an adenovirus vector expressing human CYP3A4

Kuno S., Sakurai F., Shimizu K., Matsumura N., Kim S., Watanabe H., Tashiro K., Tachibana M., Yokoi T., Mizuguchi H.

Drug Metab. Pharmacokinet., 29, 296-304 (2014)

PubMed

HHEX promotes hepatic-lineage specification through the negative regulation of eomesodermin

Watanabe H.#, Takayama K.#, Inamura M., Tachibana M., Mimura N., Tashiro K., Nagamoto Y., Sakurai F., Kawabata K., Furue MK., Mizuguchi H. #These authors equally contributed to this work.

PLoS One, 9, e90791 (2014)

PubMed

Enhanced expression of the β4-galactosyltransferase 2 gene impairs mammalian tumor growth

Tagawa M., Shirane K., Yu L., Sato T., Furukawa S., Mizuguchi H., Kuji R., Kawamura K., Takahashi N., Kato K., Hayakawa S., Sawada S., Furukawa K.

Cancer Gene Ther., 21, 219-227 (2014)

PubMed

Polyethyleneimine-coating enhances adenoviral transduction of mesenchymal stem cells

Yao X, Zhou N, Wan L, Su X, Sun Z, Mizuguchi H., Yoshioka Y, Nakagawa S, Zhao RC, Gao JQ.

Biochem. Biophys. Res. Commun., 447, 383-387 (2014)

PubMed

Suppression of leaky expression of adenovirus genes by insertion of microRNA-targeted sequences in the replication-incompetent adenovirus vector genome

Shimizu K., Sakurai F., Tomita K., Nagamoto Y., Nakamura S., Katayama K., Tachibana M., Kawabata K., Mizuguchi H.

Mol. Ther. Methods Clin. Dev., 1, 14035 (2014)

PubMed

目次に戻る

大阪大学大学院薬学研究科分子生物学分野

Laboratory of Biochemistry and Molecular Biology

Graduate School of Pharmaceutical Sciences, Osaka University

業績｜論文・出版物｜目次｜ALL