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業績｜論文・出版物｜目次｜
 

2024

Generation and application of CES1-knockout Tet-Off-regulated CYP3A4 and UGT1A1-expressing Caco-2 cells.

Murata M., Okada K., Takahashi M., Ueyama-Toba Y., Ito S., Mizuguchi H.

Toxicol Lett., 401, 158-169 (2024)

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Development of a hepatic differentiation method in 2D culture from primary human hepatocyte-derived organoids for pharmaceutical research.

Ueyama-Toba Y., Tong Y., Yokota J., Murai K., Hikita H., Eguchi H., Takehara T., Mizuguchi H.

iScience, 27, 110778 (2024)

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Development of a novel adenovirus serotype 35 vector vaccine possessing an RGD peptide in the fiber knob and the E4 orf 4, 6, and 6/7 regions of adenovirus serotype 5

Onishi R., Ikemoto S., Shiota A., Tsukamoto T., Asayama A., Tachibana M., Sakurai F., Mizuguchi H.

Int J Pharm., 662, 124480 (2024)

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Transplacental delivery of factor IX Fc-fusion protein ameliorates bleeding phenotype of newborn hemophilia B mice

Sakurai F., Iizuka S., Tsukamoto T., Shiota A., Shimizu K., Ohashi K., Mizuguchi H.

J Control Release, 374, 415-424 (2024)

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Small extracellular vesicles carrying reovirus, tumor antigens, interferon-β, and damage-associated molecular patterns for efficient tumor treatment

Shuwari N., Inoue C., Ishigami I., Jingushi K., Kamiya M., Kawakami S., Tsujikawa K., Tachibana M., Mizuguchi H., Sakurai F.

J Control Release, 374, 89-102 (2024)

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Functional intestinal monolayers from organoids derived from human iPS cells for drug discovery research

Inui T., Uraya Y., Yokota J., Yamashita T., Kawai K., Okada K., Ueyama-Toba Y., Mizuguchi H.

Stem Cell Research & Therapy, 15, 57 (2024)

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Development of an Improved Adenovirus Vector and Its Application to the Treatment of Lifestyle-Related Diseases

Shimzu K.

Biol Pharm Bull., 47, 886-894 (2024)

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Efficient hepatocyte differentiation of primary human hepatocyte-derived organoids using three dimensional nanofibers (HYDROX) and their possible application in hepatotoxicity research

Tong Y., Ueyama-Toba Y., Yokota Y., Matsui H., Kanai M., Mizuguchi H.

Sci. Rep., 14, 10846 (2024)

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Heterogenous gene expression of bicellular and tricellular tight junction-sealing components in the human intestinal tract.

Tachibana K., Bai L., Sugimura S., Fujioka H., Kishimoto W., Mizuguchi H., Nakase H., Kondoh M.

Biol. Pharm. Bull., 47, 1209-1217 (2024)

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A general fluorescence off/on strategy for fluorogenic probes: Steric repulsion-induced twisted intramolecular charge transfer (sr-TICT).

Hanaoka K., Ikeno T., Iwaki S., Deguchi S., Takayama K., Mizuguchi H., Tao F., Kojima N., Ohno H., Sasaki E., Komatsu T., Ueno T., Maeda K., Kusuhara H., Urano Y.

Sci. Adv., 10, eadi8847 (2024)

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Overexpression of lysophospholipid acyltransferase, LPLAT10/LPCAT4/LPEAT2, in the mouse liver increases glucose-stimulated insulin secretion.

Shimizu K., Ono M., Mikamoto T., Urayama Y., Yoshida S., Hase T., Michinaga S., Nakanishi H., Iwasaki M., Terada T., Sakurai F., Mizuguchi H., Shindou H., Tomita K., Nishinaka T.

FASEB J., 38, e23425 (2024)

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Establishment of human intestinal organoids derived from commercially available cryopreserved intestinal epithelium and evaluation for pharmacokinetic study

Okada K., Yokota J., Yamashita T., Inui T., Kishimoto W., Nakase H., Mizuguchi H.,

Drug Metab Pharmacokinet., 54, 100532 (2024)

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