top of page

 
業績|論文・出版物|目次
 

2024

Generation and application of CES1-knockout Tet-Off-regulated CYP3A4 and UGT1A1-expressing Caco-2 cells.

Murata M., Okada K., Takahashi M., Ueyama-Toba Y., Ito S., Mizuguchi H.

Toxicol Lett., 401, 158-169 (2024)

(外部サイトへリンク)

Development of a hepatic differentiation method in 2D culture from primary human hepatocyte-derived organoids for pharmaceutical research.

Ueyama-Toba Y., Tong Y., Yokota J., Murai K., Hikita H., Eguchi H., Takehara T., Mizuguchi H.

iScience, 27, 110778 (2024)

(外部サイトへリンク)

Development of a novel adenovirus serotype 35 vector vaccine possessing an RGD peptide in the fiber knob and the E4 orf 4, 6, and 6/7 regions of adenovirus serotype 5

Onishi R., Ikemoto S., Shiota A., Tsukamoto T., Asayama A., Tachibana M., Sakurai F., Mizuguchi H.

Int J Pharm., 662, 124480 (2024)

(外部サイトへリンク)

Transplacental delivery of factor IX Fc-fusion protein ameliorates bleeding phenotype of newborn hemophilia B mice

Sakurai F., Iizuka S., Tsukamoto T., Shiota A., Shimizu K., Ohashi K., Mizuguchi H.

J Control Release, 374, 415-424 (2024)

(外部サイトへリンク)

Small extracellular vesicles carrying reovirus, tumor antigens, interferon-β, and damage-associated molecular patterns for efficient tumor treatment

Shuwari N., Inoue C., Ishigami I., Jingushi K., Kamiya M., Kawakami S., Tsujikawa K., Tachibana M., Mizuguchi H., Sakurai F.

J Control Release, 374, 89-102 (2024)

(外部サイトへリンク)

Efficient hepatocyte differentiation of primary human hepatocyte-derived organoids using three dimensional nanofibers (HYDROX) and their possible application in hepatotoxicity research

Tong Y., Ueyama-Toba Y., Yokota Y., Matsui H., Kanai M., Mizuguchi H.

Sci. Rep., 14, 10846 (2024)

(外部サイトへリンク)

Development of an Improved Adenovirus Vector and Its Application to the Treatment of Lifestyle-Related Diseases

Shimzu K.

Biol Pharm Bull., 47, 886-894 (2024)

(外部サイトへリンク)

Functional intestinal monolayers from organoids derived from human iPS cells for drug discovery research

Inui T., Uraya Y., Yokota J., Yamashita T., Kawai K., Okada K., Ueyama-Toba Y., Mizuguchi H.

Stem Cell Research & Therapy, 15, 57 (2024)

(外部サイトへリンク)

Heterogenous gene expression of bicellular and tricellular tight junction-sealing components in the human intestinal tract.

Tachibana K., Bai L., Sugimura S., Fujioka H., Kishimoto W., Mizuguchi H., Nakase H., Kondoh M.

Biol. Pharm. Bull., 47, 1209-1217 (2024)

(外部サイトへリンク)

A general fluorescence off/on strategy for fluorogenic probes: Steric repulsion-induced twisted intramolecular charge transfer (sr-TICT).

Hanaoka K., Ikeno T., Iwaki S., Deguchi S., Takayama K., Mizuguchi H., Tao F., Kojima N., Ohno H., Sasaki E., Komatsu T., Ueno T., Maeda K., Kusuhara H., Urano Y.

Sci. Adv., 10, eadi8847 (2024)

(外部サイトへリンク)

Overexpression of lysophospholipid acyltransferase, LPLAT10/LPCAT4/LPEAT2, in the mouse liver increases glucose-stimulated insulin secretion.

Shimizu K., Ono M., Mikamoto T., Urayama Y., Yoshida S., Hase T., Michinaga S., Nakanishi H., Iwasaki M., Terada T., Sakurai F., Mizuguchi H., Shindou H., Tomita K., Nishinaka T.

FASEB J., 38, e23425 (2024)

(外部サイトへリンク)

Establishment of human intestinal organoids derived from commercially available cryopreserved intestinal epithelium and evaluation for pharmacokinetic study

Okada K., Yokota J., Yamashita T., Inui T., Kishimoto W., Nakase H., Mizuguchi H.,

Drug Metab Pharmacokinet., 54, 100532 (2024)

(外部サイトへリンク)

大阪大学大学院 薬学研究科 分子生物学分野 

〒565-0871 大阪府吹田市山田丘1-6 大阪大学 大学院薬学研究科・薬学部 1号館 4階

TEL: 06-6879-8185 FAX: 06-6879-8187

Copyright© Laboratory of Biochemistry and Molecular Biology, Graduate School and School of Pharmaceutical Sciences, Osaka University

directed by Prof. Hiroyuki Mizuguchi

  • 分子生物学分野 | 阪大 | 薬学 | 生化 twitter
bottom of page