業績|論文・出版物|目次|
2021
Monolayer platform using human biopsy-derived duodenal organoids for pharmaceutical research
Yamashita T., Inui T., Yokota J., Kawakami K., Morinaga G., Takatani M., Hirayama D., Nomoto R., Ito K., Cui Y., Ruez S., Harada K., Kishimoto W., Nakase H., Mizuguchi H.
Mol. Ther. Methods Clin. Dev., 22, 263-278 (2021)
Transduction properties of an adenovirus vector containing sequences complementary to a liver-specific microRNA, miR-122a, in the 3'-untranslated region of the E4 gene in human hepatocytes from chimeric mice with humanized liver.
Sakurai F., Tsukamoto T., Ono R., Nishimae F., Shiota A., Iizuka S., Shimizu K., Sakai E., Ishida Y., Tateno C., Chayama K., Mizuguchi H.
Biol. Pharm. Bull., 44, 1506-1513 (2021)
Generation of Tetrafluoroethylene-Propylene Elastomer-Based Microfluidic Devices for Drug Toxicity and Metabolism Studies.
Sano E., Deguchi S., Matsuoka N., Tsuda M., Wang M., Kosugi K., Mori C., Yagi K., Wada A., Yamasaki S., Kawai T., Yodogawa M, Mizuguchi H., Nakazawa N., Yamashita F., Torisawa Y.S., Takayama K.
ACS omega, 6, 24859-24865 (2021)
Usability of Polydimethylsiloxane-Based Microfluidic Devices in Pharmaceutical Research Using Human Hepatocytes.
Deguchi S., Tsuda M., Kosugi K., Sakamoto A., Mimura N., Negoro R., Sano E., Nobe T., Maeda K., Kusuhara H., Mizuguchi H., Yamashita F., Torisawa Y.S., Takayama K.
ACS Biomater. Sci. Eng., 7, 3648-3657 (2021)
A selective cytotoxic adenovirus vector for concentration of pluripotent stem cells in human pluripotent stem cell-derived neural progenitor cells.
Hirai T., Kono K., Sawada R., Kuroda T., Yasuda S., Matsuyama S., Matsuyama A., Koizumi N., Utoguchi N., Mizuguchi H., Sato Y.
Sci. Rep., 11, 11407 (2021)
In Vitro Model for a Drug Assessment of Cytochrome P450 Family 3 Subfamily A Member 4 Substrates Using Human Induced Pluripotent Stem Cells and Genome Editing Technology.
Deguchi S., Shintani T., Harada K., Okamoto T., Takemura A., Hirata K., Ito K., Takayama K., Mizuguchi H.
Hepatol.?Commun., 5, 1385-1399 (2021)