業績|論文・出版物|

2019

Establishment of SLC15A1/PEPT1-knockout human induced pluripotent stem cell line for intestinal drug absorption studies

Kawai K., Negoro R., Ichikawa M., Yamashita T., Deguchi S., Harada K., Hirata K., Takayama K., Mizuguchi H.
Mol. Ther. Methods Clin. Dev., 17, 49-57 (2019)

Efficient generation of adenovirus vectors carrying the Clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR associated proteins (Cas)12a system by suppressing Cas12a expression in packaging cells

Tsukamoto T., Sakai E., Nishimae F., Sakurai F., Mizuguchi H.
J. Biotech., 304, 1-9 (2019)

Generation of human iPS cell-derived intestinal epithelial cell monolayers by CDX2 transduction

Takayama K., Negoro R., Yamashita T., Kawai K., Ichikawa M., Mori T., Nakatsu N., Harada K., Ito S., Yamada H., Yamaura Y., Hirata K., Ishida S., Mizuguchi H.
Cell. Mol. Gastroenterol. Hepatol., 8, 513-526 (2019)

miR-27b-mediated suppression of aquaporin-11 expression in hepatocytes reduces HCV genomic RNA levels but not viral titers

Sakurai F.#, Hashimoto R.#, Inoue C., Wakabayashi K., Tsukamoto T., Taracena-Gándara M., Imaizumi T., Sakai E., Itsuki K., Sakamoto N., Wakita T., Mizuguchi H. #These authors equally contributed to this work.
Virology Journal, 16, 58 (2019)

Modeling of hepatic drug metabolism and responses in CYP2C19 poor metabolizer using genetically manipulated human iPS cells

Deguchi S., Yamashita T., Igai K., Harada K., Toba Y., Hirata K., Takayama K., Mizuguchi H.
Drug Metab. Dispos., 47, 632-638 (2019)

FGF signal is not required for hepatoblast differentiation of human iPS cells

Toba Y., Kiso A., Nakamae S., Sakurai F., Takayama K., Mizuguchi H.
Sci. Rep., 9, 3713 (2019)

Development of selective cytotoxic viral vectors for concentration of undifferentiated cells in cardiomyocytes derived from human induced pluripotent stem cells

Kono K., Sawada R., Kuroda T., Yasuda S., Matsuyama S., Matsuyama A., Mizuguchi H., Sato Y.
Sci. Rep., 9, 3630 (2019)

A microRNA derived from adenovirus virus-associated RNAII promotes virus infection via post-transcriptional gene silencing

Wakabayashi K.#, Machitani M.#, Tachibana M., Sakurai F., Mizuguchi H. #These authors equally contributed to this work.
J. Virol., 93, e01265-18 (2019)

Pharmaceutical research for inherited metabolic disorders of the liver using human induced pluripotent stem cell and genome editing technologies

Yamashita T., Takayama K., Hori M., Harada-Shiba M., Mizuguchi H.
Biol. Pharm. Bull., 42, 312-318 (2019)

アデノウイルス由来小分子RNAによるウイルス増殖促進機構の解明と遺伝子組換えウイルスへの応用

若林圭作, 櫻井文教, 水口裕之
生産と技術, 71, 10-14 (2019)