大阪大学大学院 薬学研究科 分子生物学分野
Laboratory of Biochemistry and Molecular Biology
Graduate School of Pharmaceutical Sciences, Osaka University
業績｜論文・出版物｜目次｜
2018
Systemically administered reovirus-induced down-regulation of hypoxia inducible factor-1α in subcutaneous tumors
Hotani T., Mizuguchi H., Sakurai F.
Mol. Ther. Oncolytics, 12, 162-172 (2018)
Efficient generation of small intestinal epithelial-like cells from human iPS cells for drug absorption and metabolism studies
Negoro R., Takayama K., Kawai K., Harada K., Sakurai F., Hirata K., Mizuguchi H.
Stem Cell Rep., 11, 1539-1550 (2018)
Optimal human iPS cell culture method for efficient hepatic differentiation
Matoba N.#, Yamashita T.#, Takayama K., Sakurai F., Mizuguchi H. #These authors equally contributed to this work.
Differentiation, 104, 13-21 (2018)
LY341495, an mGluR2/3 antagonist, regulates the immunosuppressive function of myeloid-derived suppressor cells and inhibits melanoma tumor growth
Morikawa N., Tachibana M., Ago Y., Goda H., Sakurai F., Mizuguchi H.
Biol. Pharm. Bull., 41, 1866-1869 (2018)
Antibodies against adenovirus fiber and penton base proteins inhibit adenovirus vector-mediated transduction in the liver following systemic administration
Tomita K., Sakurai F., Iizuka S., Hemmi M., Wakabayashi K., Tachibana M., Katayama K., Kamada H., Mizuguchi H.
Sci. Rep., 8, 12315 (2018)
Generation of the adenovirus vector-mediated CRISPR/Cpf1 system and the application for primary human hepatocytes prepared from humanized mice with chimeric liver
Tsukamoto T., Sakai E., Iizuka S., Taracena-Gándara M., Sakurai F., Mizuguchi H.
Biol. Pharm. Bull., 41, 1089-1095 (2018)
Enrichment of high-functioning human iPS cell-derived hepatocyte-like cells for pharmaceutical research
Takayama K., Hagihara Y., Toba Y., Sekiguchi K., Sakurai F., Mizuguchi H.
Biomaterials, 161, 24-32 (2018)
Oncolytic reovirus inhibits immunosuppressive activity of myeloid-derived suppressor cells in a TLR3-dependent manner
Katayama Y., Tachibana M., Kurisu N., Oya Y., Terasawa Y., Goda H., Kobiyama K., Ishii K., Akira S., Mizuguchi H., Sakurai F.
J. Immunol., 200, 2987-2999 (2018)
Nanaomycin A treatment promotes hepatoblast differentiation from human iPS cells
Nakamae S.#, Toba Y.#, Takayama K., Sakurai F., Mizuguchi H. #These authors equally contributed to this work.
Stem Cells Dev., 27, 405-414 (2018)
Billion-scale production of hepatocyte-like cells from human iPS cells
Yamashita T., Takayama K., Sakurai F., Mizuguchi H.
Biochem. Biophys. Res. Commun., 496, 1269–1275 (2018)
Occludin as a functional marker of vascular endothelial cells on tube-forming activity
Kanayasu-Toyoda T., Ishii-Watabe A., Kikuchi Y., Kitagawa H., Suzuki H., Tamura H., Tada M., Suzuki T., Mizuguchi H., Yamaguchi T.
J. Cell. Physiol., 233, 1700-1711 (2018)
Generation of optogenetically modified adenovirus vector for spatiotemporally controllable gene therapy
Takayama K., Mizuguchi H.
ACS Chem. Biol., 13, 449–454 (2018)
Detection of CTCs in cervical cancer using a conditionally replicative adenovirus targeting telomerase-positive cells
Takakura M., Matsumoto T., Nakamura M., Mizumoto Y., Myojyo S., Yamazaki R., Iwadare J., Bono Y., Orisaka S., Obata T., Izuka T., Kagami K., Nakayama K., Hayakawa H., Sakurai F., Mizuguchi H., Urata Y., Fujiwara T., Kyo S., Sasagawa T., Fujiwara H.
Cancer Sci., 109, 231-240 (2018)
Human iPS cell-based liver-like tissue engineering at extrahepatic sites in mice as a new cell therapy for hemophilia B
Okamoto R.#, Takayama K.#, Akita N.#, Nagamoto Y., Hosokawa D., Iizuka S., Sakurai F., Suemizu H., Ohashi K., Mizuguchi H. #These authors equally contributed to this work.
Cell Transplant., 27, 299-309 (2018)