業績｜論文・出版物｜目次｜

2016

Transplantation of a human iPSC-derived hepatocyte sheet increases survival in mice with acute liver failure

Nagamoto Y., Takayama K., Ohashi K., Okamoto R., Sakurai F., Tachibana M., Kawabata K., Mizuguchi H.

J. Hepatol., 64, 1068-1075 (2016)

NF-kB promotes leaky expression of adenovirus genes in a replication-incompetent adenovirus vector

Machitani M.#, Sakurai F.#, Wakabayashi K., Nakatani K., Shimizu K., Tachibana M., Mizuguchi H. #These authors equally contributed to this work.

Sci. Rep., 6, 19922 (2016)

PubMed

Efficient detection of human circulating tumor cells without significant production of false-positive cells by a novel conditionally replicating adenovirus

Sakurai F., Narii N., Tomita K., Togo S., Takahashi K., Machitani M., Tachibana M., Ouchi M., Katagiri N., Urata Y., Fujiwara T., Mizuguchi H.

Mol. Ther. Methods Clin. Dev., 3, 16001 (2016)

PubMed

Dicer functions as an antiviral system against human adenoviruses via cleavage of adenovirus-encoded noncoding RNA

Machitani M.#, Sakurai F.#, Wakabayashi K., Tomita K., Tachibana M., Mizuguchi H. #These authors equally contributed to this work.

Sci. Rep., 6, 27598 (2016)

PubMed

Laminin 411 and 511 promote the cholangiocyte differentiation of human induced pluripotent stem cells

Takayama K.#, Mitani S.#, Nagamoto Y., Sakurai F., Tachibana M., Taniguchi Y., Sakaguchi K., Mizuguchi H. #These authors equally contributed to this work.

Biochem. Biophys. Res. Commun., 474, 91-96 (2016)

PubMed

Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells

Negoro R.#, Takayama K.#, Nagamoto Y., Sakurai F., Tachibana M., Mizuguchi H. #These authors equally contributed to this work.

Biochem. Biophys. Res. Commun., 472, 631-636 (2016)

PubMed

Hepatic maturation of human iPS cell-derived hepatocyte-like cells by ATF5, c/EBPα, and PROX1 transduction

Nakamori D.#, Takayama K.#, Nagamoto Y., Mitani S., Sakurai F., Tachibana M., Mizuguchi H. #These authors equally contributed to this work.

Biochem. Biophys. Res. Commun., 469, 424-429 (2016)

PubMed

TANK-binding kinase 1-dependent or -independent signaling elicits the cell type-specific innate immune responses induced by the adenovirus vector

Tsuzuki S.#, Tachibana M.#, Hemmi M., Yamaguchi T., Shoji M., Sakurai F., Kobiyama K., Kawabata K., Ishii K.J., Akira S., Mizuguchi H. #These authors equally contributed to this work.

Int. Immunol., 28, 105-115 (2016)

PubMed

Adenovirus vector-based incorporation of a photo-cross-linkable amino acid into proteins in human primary cells and cancerous cell lines

Kita A., Hino N., Higashi S., Hirota K., Narumi R., Adachi J., Takafuji K., Ishimoto K., Okada Y., Sakamoto K., Tomonaga T., Takashima S., Mizuguchi H., Doi T.

Sci. Rep., 6, 36946 (2016)

PubMed

Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells

Yanagihara K., Liu Y., Kanie K., Takayama K., Kokunugi M., Hirata M., Fukuda T., Suga M., Nikawa H., Mizuguchi H., Kato R., Furue M.K.

Stem Cells Dev., 25, 1884-1897 (2016)

PubMed

Coating with Spermine-Pullulan Polymer Enhances Adenoviral Transduction of Mesenchymal Stem Cells

Wan L., Yao X., Faiola F., Liu B., Zhang T., Tabata Y., Mizuguchi H., Nakagawa S., Gao J.Q, Zhao R.C.

Int. J. Nanomed., 11, 6763-6769 (2016)

PubMed

Tumor-specific delivery of biologics by a novel T-cell line HOZOT

Onishi T., Tazawa H., Hashimoto Y., Takeuchi M., Otani T., Nakamura S., Sakurai F., Mizuguchi H., Kishimoto H., Umeda Y., Shirakawa Y., Urata Y., Kagawa S., Fujiwara T.

Sci. Rep., 6, 38060 (2016)

PubMed

Expression of HIF-1α ODD domain fused canine caspase 3 by EGFR promoter-driven adenovirus vector induces cytotoxicity in canine breast tumor cells under hypoxia

Okamoto M., Asamura A., Tanaka K., Soeda T., Watanabe K., Mizuguchi H., Ikeda T.

Vet. Res. Commun., 40, 131-139 (2016)

PubMed

Targeted photodynamic virotherapy armed with a genetically encoded photosensitizer

Takehara K., Tazawa H., Okada N., Hashimoto Y., Kikuchi S., Kuroda S., Kishimoto H., Shirakawa Y., Narii N., Mizuguchi H., Urata Y., Kagawa S., Fujiwara T.

Mol. Cancer Ther., 15, 199-208 (2016)

PubMed

Adenoviral Vector Construction II: Bacterial Systems

Hemmi M., Mizuguchi H.

Adenoviral Vectors for Gene Therapy (Second Edition), Academic Press, 113-137 (2016)

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ヒトiPS細胞から肝細胞への分化誘導と毒性評価系への応用

水口裕之, 高山和雄

SCAS NEWS 2016-Ⅱ, 株式会社住化分析センター, 3-7 (2016)

WebSite

ヒトiPS細胞を用いた薬剤評価のための肝細胞の作製

水口裕之, 高山和雄