大阪大学大学院 薬学研究科 分子生物学分野
Laboratory of Biochemistry and Molecular Biology
Graduate School of Pharmaceutical Sciences, Osaka University
業績｜論文・出版物｜目次｜
2016
Transplantation of a human iPSC-derived hepatocyte sheet increases survival in mice with acute liver failure
Nagamoto Y., Takayama K., Ohashi K., Okamoto R., Sakurai F., Tachibana M., Kawabata K., Mizuguchi H.
J. Hepatol., 64, 1068-1075 (2016)
NF-kB promotes leaky expression of adenovirus genes in a replication-incompetent adenovirus vector
Machitani M.#, Sakurai F.#, Wakabayashi K., Nakatani K., Shimizu K., Tachibana M., Mizuguchi H. #These authors equally contributed to this work.
Sci. Rep., 6, 19922 (2016)
Efficient detection of human circulating tumor cells without significant production of false-positive cells by a novel conditionally replicating adenovirus
Sakurai F., Narii N., Tomita K., Togo S., Takahashi K., Machitani M., Tachibana M., Ouchi M., Katagiri N., Urata Y., Fujiwara T., Mizuguchi H.
Mol. Ther. Methods Clin. Dev., 3, 16001 (2016)
Dicer functions as an antiviral system against human adenoviruses via cleavage of adenovirus-encoded noncoding RNA
Machitani M.#, Sakurai F.#, Wakabayashi K., Tomita K., Tachibana M., Mizuguchi H. #These authors equally contributed to this work.
Sci. Rep., 6, 27598 (2016)
Laminin 411 and 511 promote the cholangiocyte differentiation of human induced pluripotent stem cells
Takayama K.#, Mitani S.#, Nagamoto Y., Sakurai F., Tachibana M., Taniguchi Y., Sakaguchi K., Mizuguchi H. #These authors equally contributed to this work.
Biochem. Biophys. Res. Commun., 474, 91-96 (2016)
Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells
Negoro R.#, Takayama K.#, Nagamoto Y., Sakurai F., Tachibana M., Mizuguchi H. #These authors equally contributed to this work.
Biochem. Biophys. Res. Commun., 472, 631-636 (2016)
Hepatic maturation of human iPS cell-derived hepatocyte-like cells by ATF5, c/EBPα, and PROX1 transduction
Nakamori D.#, Takayama K.#, Nagamoto Y., Mitani S., Sakurai F., Tachibana M., Mizuguchi H. #These authors equally contributed to this work.
Biochem. Biophys. Res. Commun., 469, 424-429 (2016)
TANK-binding kinase 1-dependent or -independent signaling elicits the cell type-specific innate immune responses induced by the adenovirus vector
Tsuzuki S.#, Tachibana M.#, Hemmi M., Yamaguchi T., Shoji M., Sakurai F., Kobiyama K., Kawabata K., Ishii K.J., Akira S., Mizuguchi H. #These authors equally contributed to this work.
Int. Immunol., 28, 105-115 (2016)
Adenovirus vector-based incorporation of a photo-cross-linkable amino acid into proteins in human primary cells and cancerous cell lines
Kita A., Hino N., Higashi S., Hirota K., Narumi R., Adachi J., Takafuji K., Ishimoto K., Okada Y., Sakamoto K., Tomonaga T., Takashima S., Mizuguchi H., Doi T.
Sci. Rep., 6, 36946 (2016)
Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells
Yanagihara K., Liu Y., Kanie K., Takayama K., Kokunugi M., Hirata M., Fukuda T., Suga M., Nikawa H., Mizuguchi H., Kato R., Furue M.K.
Stem Cells Dev., 25, 1884-1897 (2016)
Coating with Spermine-Pullulan Polymer Enhances Adenoviral Transduction of Mesenchymal Stem Cells
Wan L., Yao X., Faiola F., Liu B., Zhang T., Tabata Y., Mizuguchi H., Nakagawa S., Gao J.Q, Zhao R.C.
Int. J. Nanomed., 11, 6763-6769 (2016)
Tumor-specific delivery of biologics by a novel T-cell line HOZOT
Onishi T., Tazawa H., Hashimoto Y., Takeuchi M., Otani T., Nakamura S., Sakurai F., Mizuguchi H., Kishimoto H., Umeda Y., Shirakawa Y., Urata Y., Kagawa S., Fujiwara T.
Sci. Rep., 6, 38060 (2016)
Expression of HIF-1α ODD domain fused canine caspase 3 by EGFR promoter-driven adenovirus vector induces cytotoxicity in canine breast tumor cells under hypoxia
Okamoto M., Asamura A., Tanaka K., Soeda T., Watanabe K., Mizuguchi H., Ikeda T.
Vet. Res. Commun., 40, 131-139 (2016)
Targeted photodynamic virotherapy armed with a genetically encoded photosensitizer
Takehara K., Tazawa H., Okada N., Hashimoto Y., Kikuchi S., Kuroda S., Kishimoto H., Shirakawa Y., Narii N., Mizuguchi H., Urata Y., Kagawa S., Fujiwara T.
Mol. Cancer Ther., 15, 199-208 (2016)
Adenoviral Vector Construction II: Bacterial Systems
Hemmi M., Mizuguchi H.
Adenoviral Vectors for Gene Therapy (Second Edition), Academic Press, 113-137 (2016)