業績｜論文・出版物｜目次｜
2011
Efficient generation of hepatoblastsfrom human ES cells and iPS cells by transient overexpression of homeobox gene HEX
Inamura M., Kawabata K., Takayama K., Tashiro K., Sakurai F., Katayama K., Toyoda M., Akutsu H., Miyagawa Y.,Okita H., Kiyokawa N., Umezawa A., Hayakawa T., Furue MK., Mizuguchi H.
Mol. Ther., 19, 400-407 (2011)
Efficient and directive generation of two distinct endoderm lineages from human ES and iPS cells by differentiation stage-specific SOX17 transduction
Takayama K., Inamura M., Kawabata K., Tashiro K., Katayama K., Hayakawa T., Furue MK., Mizuguchi H.
PLoS One, 6, e21780 (2011)
Enhanced safety profiles of the telomerase-specific replication-competent adenovirus by incorporation of normal cell-specific microRNA-targeted sequences
Sugio K., Sakurai F., Katayama K., Matsui H., Kawabata K., Kawase A., Iwaki M., Hayakawa T., Fujiwara T., Mizuguchi H.
Clin. Cancer Res., 17, 2807-2818 (2011)
Hexon-specific PEGylated adenovirus vectors utilizing avidin-biotin interaction
Suzuki-Kouyama E., Katayama K., Sakurai F., Yamaguchi T., Kurachi S., Kawabata K., Nakagawa S., Mizuguchi H.
Biomaterials, 32, 1724-1730 (2011)
Enhanced transduction efficiency of fiber-substituted adenovirus vectors by the incorporation of RGD peptides in two distinct regions of the adenovirus serotype 35 fiber knob
Matsui H., Sakurai F., Katayama K., Kurachi S., Tashiro K., Sugio K., Kawabata K., Mizuguchi H.
Virus Res., 155, 48-54 (2011)
Development of a recombinant adenovirus vector production system free of replication-competent adenovirus by utilizing a packaging size limit of the viral genome
Suzuki T., Sasaki T., Yano K., Sakurai F., Kawabata K., Kondoh M., Hayakawa T., Yagi K., Mizuguchi H.
Virus Res., 158, 154-160 (2011)
Use of human hepatocyte-like cells derived from induced pluripotent stem cells as a model for hepatocytes in hepatitis C virus infection
Yoshida T.#, Takayama K.#, Kondoh M.*, Sakurai F., Tani H., Sakamoto N., Matsuura Y., Mizuguchi H*., Yagi K*. #These authors equally contributed to this work. *Co-corresponding author.
Biochem. Biophys. Res. Commun., 416, 119-124 (2011)
An effective gene-knockdown using multiple shRNA-expressing adenovirus vectors
Motegi Y., Katayama K., Sakurai F., Kato T., Yamaguchi T., Matsui H., Takahashi M., Kawabata K., Mizuguchi H.
J. Control. Release, 153, 149-153 (2011)
Quantitative analysis of the leaky expression of adenovirus genes in cells transduced with a replication-incompetent adenovirus vector
Shimizu K., Sakurai F., Machitani M., Katayama K., Mizuguchi H.
Mol. Pharmaceutics, 8, 1430-1435 (2011)
Development of an adenovirus vector lacking the expression of virus-associated RNAs
Machitani M., Katayama K., Sakurai F., Matsui H., Yamaguchi T., Suzuki T., Miyoshi H., Kawabata K., Mizuguchi H.
J. Control. Release, 154, 285-289 (2011)
Enhanced in vivo gene transfer into the placenta using RGD fiber-mutant adenovirus vector
Katayama K., Furuki R., Yokoyama H., Kaneko M., Tachibana M., Yoshida I., Nagase H., Tanaka K., Sakurai F., Mizuguchi H., Nakagawa S., Nakanishi T.
Biomaterials, 32, 4185-4193 (2011)
Overexpression of SOCS3 exhibits preclinical antitumor activity against malignant pleural mesothelioma
Iwahori K., Serada S., Fujimoto M., Nomura S., Osaki T., Lee C.M., Mizuguchi H., Takahashi T., Ripley B., Okumura M., Kawase I., Kishimoto T., Naka T.
Int. J. Cancer, 129, 993-1005 (2011)
Adenovirus vector-mediated assay system for Hepatitis C virus replication
Yoshida T., Kondoh M., Ojima M., Mizuguchi H., Yamagishi Y., Sakamoto N., Yagi K.
Nuc. Acid Res., 39, e64 (2011)
Optimization of a microRNA expression vector for function analysis of microRNA
Furukawa N., Sakurai F., Katayama K., Seki N., Kawabata K., Mizuguchi H.
J. Control. Release, 150, 94-101 (2011)
EpCAM- and EGFR- targeted selective gene therapy for biliary cancers using Z33-fiber modified adenovirus
Kawashima R., Abei M., Fukuda K., Nakamura K., Murata T., Wakayama M., Seo E., Hasegawa N., Mizuguchi H., Obata Y., Hyodo I., Hamada H., Yokoyama K.K.
Int. J. Cancer, 129, 1244-53 (2011)
Enhanced cancer immunotherapy using STAT3-depleted dendritic cells with high Th1-inducing ability and resistance to cancer cell-derived inhibitory factors
Iwata-Kajihara T., Sumimoto H., Kawamura N., Ueda R., Takahashi T., Mizuguchi H., Miyagishi M., Takeda K., Kawakami Y.
J. Immunol., 187, 27-36 (2011)
Tumor vascular targeted delivery of polymer-conjugated adenovirus vector for cancer gene therapy
Yao X., Yoshioka Y., Morishige T., Eto Y., Narimatsu S., Kawai Y., Mizuguchi H., Gao J.Q., Mukai Y., Okada N., Nakagawa S.
Mol. Ther., 19, 1619-1625 (2011)
Adenovirus vector-derived VA-RNA-mediated innate immune responses
Machitani M., Yamaguchi T., Shimizu K., Sakurai F., Katayama K., Kawabata K., Mizuguchi H.
Pharmaceutics, 3, 38-353 (2011)
MicroRNA-regulated transgene expression system for gene therapy and virotherapy
Sakurai F., Katayama K., Mizuguchi H.
Front. Biosci., 17, 2389-2401 (2011)