業績｜論文・出版物｜目次｜

2010

Induction of type I interferon by adenovirus-encoded small RNAs

Yamaguchi T., Kawabata K., Kouyama E., Ishii K.J., Katayama K., Suzuki T., Kurachi S., Sakurai F., Akira S., Mizuguchi H.

Proc. Natl. Acad. Sci. USA, 107, 17286-17291 (2010)

PubMed

Adenovirus serotype 35 vector-induced innate immune responses in dendritic cells derived from wild-type and human CD46-transgenic mice: Comparison with a fiber-substituted Ad vector containing fiber proteins of Ad serotype 35

Sakurai, F., Nakashima, K., Yamaguchi, T., Ichinose, T., Kawabata, K., Hayakawa, T., and Mizuguchi, H.

J. Control. Release, 148, 212-218 (2010)

PubMed

Adenovirus vector-mediated efficient transduction into human embryonic and induced pluripotent stem cells

Tashiro K., Kawabata K., Inamura M., Takayama K., Furukawa N., Sakurai F., Katayama K., Hayakawa H., Furue-Kusuda M., Mizuguchi H.

Cell. Reprogram., 12, 501-507 (2010)

PubMed

Optimized PEGylated adenovirus vector reduces the anti-vector humoral immune response against adenovirus and induces a therapeutic effect against metastatic lung cancer

Eto Y., Yoshioka Y., Ishida T., Yao X., Morishige T., Narimatsu S., Mizuguchi H., Mukai Y., Okada N., Kiwada H., Nakagawa S.

Biol. Pharm. Bull., 33, 1540-1544 (2010)

PubMed

Prevention of hepatic ischemia-reperfusion injury by pre-administration of catalase-expressing adenovirus vectors

Ushitora M., Sakurai F., Yamaguchi T., Nakamura S-I., Kondoh M., Yagi K., Kawabata K., Mizuguchi H.

J. Control. Release, 142, 431-437 (2010)

PubMed

A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy

Watanabe Y., Kojima T., Kagawa S., Uno F., Hashimoto Y., Kyo S., Mizuguchi H., Tanaka N., Kawamura H., Ichimaru D., Urata Y., Fujiwara T.

Oncogene, 29, 1145-1154 (2010)

PubMed

A fiber modified adenovirus vector that targets to the EphrinA2 receptor reveals enhanced gene transfer to ex vivo pancreatic cancer

Van Geer M.A., Brevoord D., Kuhlmann K.F., Bakker C.T., Mizuguchi H., Wesseling J.G., Ten Kate F.J., Gouma D.J., Oude Elferink R.P., Bosma P.J.

Int. J. Oncol., 36, 233-44 (2010)

PubMed

Comparison of the anti-tumor activity of native, secreted, and membrane-bound LIGHT in mouse tumor models

Morishige T., Yoshioka Y., Tanabe A., Yao X., Mizuguchi H., Tsunoda S., Tsutsumi Y., Mukai Y., Okada N., Nakagawa S.

Int. Immunopharmacol., 10, 26-33 (2010)

PubMed

In vivo biological purging for lymph node metastasis of human colorectal cancer by telomerase-specific oncolytic virotherapy

Kojima T., Watanabe Y., Hashimoto Y., Kuroda S., Yamasaki Y., Yano S., Ouchi M., Tazawa H., Uno F., Kagawa S., Kyo S., Mizuguchi H., Urata Y., Tanaka N., Fujiwara T.

Ann. Surg., 251, 1079-1086 (2010)

PubMed

Particle tracking of intracellular trafficking of octaarginine-modified liposomes: a comparative study with adenovirus

Akita H., Enoto K., Masuda T., Mizuguchi H., Tani T., Harashima H.

Mol. Ther., 18, 955-964 (2010)

PubMed

Co-administration of viral vector-based vaccines suppresses antigen-specific effector CD8 T cells

Yashima S., Yoshizaki S., Shinoda K., Yoshida A., Kondo A., Mizuguchi H., Ryo A., Okuda K., Shimada M.

Vaccine, 28, 3257-3264 (2010)

PubMed

Claudin-4-targeting of diphtheria toxin fragment A using a C-terminal fragment of Clostridium perfringens enterotoxin

Kakutani H., Kondoh M., Saeki R., Fujii M., Watanabe Y., Mizuguchi H., Yagi K.

Eur. J. Pharm. Biopharm., 75, 213-217 (2010)

PubMed

Adenovirus vector covalently conjugated to polyethylene glycol with a cancer-specific promoter suppresses the tumor growth through systemic administration

Yao X., Yoshioka Y., Morishige T., Eto Y., Narimatsu S., Mizuguchi H., Mukai Y., Okada N., Nakagawa S.

Biol. Pharm. Bull., 35, 1073-1076 (2010)

PubMed

マイクロRNAによる遺伝子発現制御システムを搭載した遺伝子組換えアデノウイルスの開発

櫻井文教, 水口裕之

薬学雑誌, 日本薬学会, 130, 1497-1504 (2010)

J-STAGE

iPS細胞への遺伝子導入を用いた分化誘導の最適化

川端健二, 田代克久, 水口裕之

薬学雑誌, 日本薬学会, 130, 1527-1534 (2010)

J-STAGE

次世代アデノウイルスベクターの開発と生命科学研究への応用