Induction of type I interferon by adenovirus-encoded small RNAs

Yamaguchi T., Kawabata K., Kouyama E., Ishii K.J., Katayama K., Suzuki T., Kurachi S., Sakurai F., Akira S., Mizuguchi H.

Proc. Natl. Acad. Sci. USA, 107, 17286-17291 (2010)

Adenovirus serotype 35 vector-induced innate immune responses in dendritic cells derived from wild-type and human CD46-transgenic mice: Comparison with a fiber-substituted Ad vector containing fiber proteins of Ad serotype 35

Sakurai, F., Nakashima, K., Yamaguchi, T., Ichinose, T., Kawabata, K., Hayakawa, T., and Mizuguchi, H.

J. Control. Release, 148, 212-218 (2010)

Adenovirus vector-mediated efficient transduction into human embryonic and induced pluripotent stem cells

Tashiro K., Kawabata K., Inamura M., Takayama K., Furukawa N., Sakurai F., Katayama K., Hayakawa H., Furue-Kusuda M., Mizuguchi H.

Cell. Reprogram., 12, 501-507 (2010)

Optimized PEGylated adenovirus vector reduces the anti-vector humoral immune response against adenovirus and induces a therapeutic effect against metastatic lung cancer

Eto Y., Yoshioka Y., Ishida T., Yao X., Morishige T., Narimatsu S., Mizuguchi H., Mukai Y., Okada N., Kiwada H., Nakagawa S.

Biol. Pharm. Bull., 33, 1540-1544 (2010)

Prevention of hepatic ischemia-reperfusion injury by pre-administration of catalase-expressing adenovirus vectors

Ushitora M., Sakurai F., Yamaguchi T., Nakamura S-I., Kondoh M., Yagi K., Kawabata K., Mizuguchi H.

J. Control. Release, 142, 431-437 (2010)

A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy

Watanabe Y., Kojima T., Kagawa S., Uno F., Hashimoto Y., Kyo S., Mizuguchi H., Tanaka N., Kawamura H., Ichimaru D., Urata Y., Fujiwara T.

Oncogene, 29, 1145-1154 (2010)

A fiber modified adenovirus vector that targets to the EphrinA2 receptor reveals enhanced gene transfer to ex vivo pancreatic cancer

Van Geer M.A., Brevoord D., Kuhlmann K.F., Bakker C.T., Mizuguchi H., Wesseling J.G., Ten Kate F.J., Gouma D.J., Oude Elferink R.P., Bosma P.J.

Int. J. Oncol., 36, 233-44 (2010)

Comparison of the anti-tumor activity of native, secreted, and membrane-bound LIGHT in mouse tumor models

Morishige T., Yoshioka Y., Tanabe A., Yao X., Mizuguchi H., Tsunoda S., Tsutsumi Y., Mukai Y., Okada N., Nakagawa S.

Int. Immunopharmacol., 10, 26-33 (2010)

In vivo biological purging for lymph node metastasis of human colorectal cancer by telomerase-specific oncolytic virotherapy

Kojima T., Watanabe Y., Hashimoto Y., Kuroda S., Yamasaki Y., Yano S., Ouchi M., Tazawa H., Uno F., Kagawa S., Kyo S., Mizuguchi H., Urata Y., Tanaka N., Fujiwara T.

Ann. Surg., 251, 1079-1086 (2010)

Particle tracking of intracellular trafficking of octaarginine-modified liposomes: a comparative study with adenovirus

Akita H., Enoto K., Masuda T., Mizuguchi H., Tani T., Harashima H.

Mol. Ther., 18, 955-964 (2010)

Co-administration of viral vector-based vaccines suppresses antigen-specific effector CD8 T cells

Yashima S., Yoshizaki S., Shinoda K., Yoshida A., Kondo A., Mizuguchi H., Ryo A., Okuda K., Shimada M.

Vaccine, 28, 3257-3264 (2010)

Claudin-4-targeting of diphtheria toxin fragment A using a C-terminal fragment of Clostridium perfringens enterotoxin

Kakutani H., Kondoh M., Saeki R., Fujii M., Watanabe Y., Mizuguchi H., Yagi K.

Eur. J. Pharm. Biopharm., 75, 213-217 (2010)

Adenovirus vector covalently conjugated to polyethylene glycol with a cancer-specific promoter suppresses the tumor growth through systemic administration

Yao X., Yoshioka Y., Morishige T., Eto Y., Narimatsu S., Mizuguchi H., Mukai Y., Okada N., Nakagawa S.

Biol. Pharm. Bull., 35, 1073-1076 (2010)

マイクロRNAによる遺伝子発現制御システムを搭載した遺伝子組換えアデノウイルスの開発

櫻井文教, 水口裕之

薬学雑誌, 日本薬学会, 130, 1497-1504 (2010)

iPS細胞への遺伝子導入を用いた分化誘導の最適化

川端健二, 田代克久, 水口裕之

薬学雑誌, 日本薬学会, 130, 1527-1534 (2010)

次世代アデノウイルスベクターの開発と生命科学研究への応用

水口裕之

Drug Delivery System, 日本DDS学会, 25, 493-503 (2010)