Development of fiber-substituted adenovirus vectors containing foreign peptides in the adenovirus serotype 35 fiber knob

Matsui H., Sakurai F., Kurachi S., Tashiro K., Sugio K., Kawabata K., Yamanishi K., Mizuguchi H.

Gene Ther., 16, 1050-1057 (2009)

Efficient adipocyte and osteoblast differentiation from mouse induced pluripotent stem cells by adenoviral transduction

Tashiro K., Inamura M., Kawabata K., Sakurai F., Yamanishi K., Hayakawa T., Mizuguchi H.

Stem Cells, 27, 102-1811 (2009)

Systemic administration of a PEGylated adenovirus vector with a cancer-specific promoter is effective in a mouse model of metastasis

Yao X., Yoshioka Y., Morishige T., Eto Y., Watanabe H., Okada Y., Mizuguchi H., Mukai Y., Okada N., Nakagawa S.

Gene Ther., 16, 1395-404 (2009)

A simple biological imaging system for detecting viable human circulating tumor cells

Kojima T., Hashimoto Y., Watanabe Y., Kagawa S., Uno F., Kuroda S., Tazawa H., Kyo S., Mizuguchi H., Urata Y., Tanaka N., Fujiwara T.

J. Clin. Invest., 119, 3172-3181 (2009)

Intratracheal delivery of CX3CL1-expressing mesenchymal stem cells to multiple lung tumors

Xin H., Sun R., Kanehira M., Takahata T., Itoh J., Mizuguchi H., Saijo Y.

Mol. Med., 15, 321-327 (2009)

Improved gene transfer into renal carcinoma cells using adenovirus vector containing RGD motif

Terao S., Acharya B., Suzuki T., Aoi T., Naoe M., Hamada K., Mizuguchi H., Gotoh A.

Anticancer Res., 29, 2997-3001 (2009)

Transduction of adenovirus vectors modified with cell penetrating peptides

Eto Y., Yoshioka Y., Asavatanabodee R., Kida S., Maeda M., Mukai Y., Mizuguchi H., Kawasaki K., Okada N., Nakagawa S.

Peptides, 30, 1548-1552 (2009)

Ephrin A2 receptor targeting does not increase adenoviral pancreatic cancer transduction in vivo

Van Geer M.A., Bakker C.T., Koizumi N., Mizuguchi H., Wesseling J.G., Oude Elferink R.P.J., Bosma P.J.

World J. Gastroenterol., 15, 2754-2762 (2009)

Telomerase-Specific Virotheranostics for Human Head and Neck Cancer

Kurihara Y., Watanabe Y., Onimatsu H., Kojima T., Shirota T., Hatori M., Liu D., Kyo S., Mizuguchi H., Urata Y., Shintani S., Fujiwara T.

Clin. Cancer Res., 15, 2335-2343 (2009)

Adenovirus serotype 35 vector-mediated transduction following direct administration into organs of nonhuman primates

Sakurai F., Nakamura S-I., Akitomo K., Shibata H., Terao K., Kawabata K., Hayakawa T., Mizuguchi H.

Gene Ther., 16, 297-302 (2009)

Efficient osteoblast differentiation from mouse bone marrow stromal cells with polylysin-modified adenovirus vectors

Tashiro K., Kondo A., Kawabata K., Sakurai H., Sakurai F., Yamanishi K., Hayakawa T., Mizuguchi H.

Biochem. Biophys. Res. Commun., 379, 127-132 (2009)

Designed recombinant adenovirus type 5 vector induced env-specific CD8+ cytotoxic T lymphocytes and cross-reactive neutralizing antibodies against human immunodeficiency virus type 1

Ura T., Yoshida A., Xin K-Q., Yoshizaki S., Yashima S., Abe S, Mizuguchi H., Okuda K.

J. Gene Med., 11, 139-149 (2009)

Adenovirus type 5 with modified hexons induces robust transgene-specific immune responses in mice with pre-existing immunity against adenovirus type 5

Abe S., Okuda K., Ura T., Kondo A., Yoshida A., Yoshizaki S., Mizuguchi H., Klinman D., Shimada M.

J. Gene Med., 11, 570-579 (2009)

Suppressive effects of sugar-modified cationic liposome/NF-κB decoy complexes on adenovirus vector-induced innate immune responses

Huang H., Sakurai F., Higuchi Y., Kawakami S., Hashida M., Kawabata K., Hayakawa T., Mizuguchi H.

J. Control. Release, 133, 139-145 (2009)

NK cells are migrated and indispensable in the anti-tumor activity induced by CCL27 gene therapy

Gao J-Q., Tsuda Y., Han M., Xu D-H., Kanagawa N., Hatanaka Y., Tani Y., Mizuguchi H., Tsutsumi Y., Mayumi T., Okada N., Nakagawa S.

Cancer Immunol. Immunother., 58, 291-299 (2009)

Effect of therapeutic immunization using Ad5/35 and MVA vectors on SIV-infection of rhesus monkeys undergoing anti-retroviral therapy

Shimada M, Wang H-B., Ino A., Xu X-P., Yoshida A., Shinoda K., Ura T., Mizuguchi H., Klinman D., Luo J-L., Bai H., Okuda K.

Gene Ther., 16, 218-228 (2009)

改良型アデノウイルスベクター開発の最前線

水口裕之

脳２１, 金芳堂, 12, 123-131 (2009)

アデノウイルスベクターの作製・増幅・精製法

水口裕之

脳２１, 金芳堂, 12, 246-251 (2009)

iPS細胞を活用した安全性・有効性評価系の構築

古江－楠田美保, 山田弘, 水口裕之

iPS細胞の産業的応用技術, シーエムシー出版, 218～224 (2009)

アデノウイルスベクターのDDS

水口裕之, 櫻井文教, 川端健二

Pharm Tech Japan, 25, 2618-2624 (2009)