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業績|論文・出版物|目次
 

2005

Efficient gene transfer into mouse embryonic stem cells with adenovirus vectors

Kawabata K., Sakurai F., Yamaguchi T., Hayakawa T., Mizuguchi H.

Mol. Ther., 12, 547-554 (2005)

(外部サイトへリンク)

Optimization of adenovirus serotype 35 vectors for efficient transduction in human hematopoietic progenitors: comparison of promoter activities

Sakurai F., Kawabata K., Yamaguchi T., Hayakawa T., Mizuguchi H.

Gene Ther., 12, 1424-1433 (2005)

(外部サイトへリンク)

Fiber-modified adenovirus vectors mediate efficient gene transfer into undifferentiated and adipogenic-differentiated human mesenchymal stem cell

Mizuguchi H., Sasaki T., Kawabata K., Sakurai F., Hayakawa T.

Biochem. Biophys. Res. Commun., 332, 1101-1106 (2005)

(外部サイトへリンク)

A trial of somatic gene targeting in vivo with an adenovirus vector

Ino A., Naito Y., Mizuguchi H., Handa N., Hayakawa T., Kobayashi I.

Genet. Vaccines Ther., 3, 8 (2005)

(外部サイトへリンク)

Efficient regulation of gene expression using self-contained fiber-modified adenovirus vectors containing the tet-off system

Mizuguchi H., Xu Z-L., Sakurai F., Kawabata K., Yamaguchi T., Hayakawa T.

J. Control. Release, 110, 202-211 (2005)

(外部サイトへリンク)

Prime-boost vaccination with plasmid DNA and a chimeric adenovirus type 5 vector with type 35 fiber induces protective immunity against HIV

Xin K-Q., Jounai N., Someya K., Honma K., Mizuguchi H., Naganawa S., Kitamura K., Hayakawa T., Saha S., Takeshita F., Okuda K., Honda M., Klinman D.M., Okuda K.

Gene Ther., 12, 1769-1777 (2005)

(外部サイトへリンク)

Role of C-terminal regions of the C-terminal fragment of Clostridium perfringens enterotoxin in its interaction with claudin-4

Takahashi A., Kondoh M., Masuyama A., Fujii M., Mizuguchi H., Horiguchi Y., Watanabe Y.

J. Control. Release, 108, 56-62 (2005)

(外部サイトへリンク)

Role of N-terminal amino acids in the absorption-enhancing effects of the C-terminal fragment of Clostridium Perfringens enterotoxin

Masuyama A., Kondoh M., Seguchi H., Takahashi A., Harada M., Fujii M., Mizuguchi H., Horiguchi Y., Watanabe Y.

J. Pharmacol. Exp. Ther., 314, 789-795 (2005)

(外部サイトへリンク)

Anti-tumor responses induced by chemokine CCL19 transfected into an ovarian carcinoma model via fiber-mutant adenovirus vector

Gao J-Q, Sugita T., Kanagawa N., Iida K., Okada N., Mizuguchi H., Nakayama T., Yoshie O., Tsutsumi Y., Mayumi T., Nakagawa S.

Biol. Pharm. Bull., 28, 1066-1070 (2005)

(外部サイトへリンク)

Transcriptional targeting of RGD fiber-mutant adenovirus vectors can improve the safety of suicide gene therapy for murine melanoma

Okada Y., Okada N., Mizuguchi H., Hayakawa T., Nakagawa S., Mayumi T.

Cancer Gene Ther., 12, 608-616 (2005)

(外部サイトへリンク)

Comparison of transgene expression mediated by several fiber-modified adenovirus vectors in trophoblast cells

Koizumi, N., Kondoh, M., Mizuguchi H., Nakanishi, T., Masuyama, A., Ida, F., Fujii, M., Hayakawa, T., Nakashima, E., Tanaka, K., Watanabe, Y.

Placenta, 26, 729-734 (2005)

(外部サイトへリンク)

PEGylated adenovirus vectors containing RGD peptides on the tip of PEG show high transduction efficiency and antibody evasion ability

Eto Y., Gao J-Q., Sekiguchi F., Kurachi S., Katayama K., Mizuguchi H., Hayakawa T., Maeda, M., Kawasaki K., Tsutsumi Y., Mayumi T., Nakagawa S.

J. Gene Med., 7, 604-612 (2005)

(外部サイトへリンク)

Enhanced oncolysis by a tropism-modified telomerase-specific replication-selective adenoviral agent OBP-405 ('Telomelysin-RGD')

Taki M., Kagawa S., Nishizaki M., Mizuguchi H., Hayakawa T., Kyo S., Nagai K., Urata Y., Tanaka N., Fujiwara T.

Oncogene, 24, 3130-3140 (2005)

(外部サイトへリンク)

Design and synthesis of a peptide-PEG transporter tool for carrying adenovirus vector into cells

Maeda M., Kida S., Hojo K., Eto Y., Gao J-Q, Kurachi S., Sekiguchi F., Mizuguchi H., Hayakawa T., Mayumi T., Nakagawa S., Kawasaki K.

Bioorg. Med. Chem. Lett., 15, 621-624 (2005)

(外部サイトへリンク)

A single intratumoral injection of a fiber-mutant adenoviral vector encoding interleukin 12 induces remarkable anti-tumor and anti-metastatic activity in mice with Meth-A fibrosarcoma

Gao J-Q, Sugita T., Kanagawa N., Iida K., Eto Y., Motomura Y., Mizuguchi H., Tsutsumi Y., Hayakawa T., Mayumi T., Nakagawa S.

Biochem. Biophys. Res. Commun., 328, 1043-1050 (2005)

(外部サイトへリンク)

Eradication of Epstein-Barr virus episome and associated inhibition of infected tumor cell growth by adenovirus vector-mediated transduction of dominant-negative EBNA1

Nasimuzzaman, M., Kuroda, M., Dohno, S., Yamamoto, T., Iwatsuki, K., Matsuzaki, S., Rashel, M., Kumita, W., Mizuguchi, H., Hayakawa, T., Nakamura, H., Taguchi, T., Wakiguchi, H., Imai, S.

Mol. Ther., 11, 578-590 (2005)

(外部サイトへリンク)

RNA interference of PPARγ using fiber-modified adenovirus vector efficiently suppresses preadipocyte-to-adipocyte differentiation in 3T3-L1 cells

Hosono T., Mizuguchi H., Katayama K., Koizumi N., Kawabata K., Yamaguchi T., Nakagawa S., Watanabe Y., Mayumi T., Hayakawa T.

Gene, 348, 157-165 (2005)

(外部サイトへリンク)

A novel strategy for the enhancement of drug absorption using a claudin modulator

Kondoh, M., Masuyama , A., Takahashi, A., Asano, N., Mizuguchi H., Koizumi, N., Fujii, M., Hayakawa, T., Horiguchi, Y., Watanabe, Y.

Mol. Pharmacol., 67, 749-756 (2005)

(外部サイトへリンク)

Gene therapy for human small cell lung carcinoma by inactivation of Skp-2 with virally mediated RNA interference

Sumimoto H., Yamagata S., Shimizu A., Miyoshi H., Mizuguchi H., Hayakawa T., Miyagishi M., Taira K., Kawakami Y.

Gene Ther., 12, 95-100 (2005)

(外部サイトへリンク)

Augmentation of the migratory ability of DC-based vaccine into regionalymph nodes by efficient CCR7 gene transduction

Okada N., Mori N., Koretomo R., Okada Y., Nakayama T., Yoshie O., Mizuguchi H., Hayakawa T., Nakagawa S., Mayumi T., Fujita T., Yamamoto A.

Gene Ther., 12, 129-139 (2005)

(外部サイトへリンク)

大阪大学大学院 薬学研究科 分子生物学分野 

〒565-0871 大阪府吹田市山田丘1-6 大阪大学 大学院薬学研究科・薬学部 1号館 4階

TEL: 06-6879-8185 FAX: 06-6879-8187

Copyright© Laboratory of Biochemistry and Molecular Biology, Graduate School and School of Pharmaceutical Sciences, Osaka University

directed by Prof. Hiroyuki Mizuguchi

  • 分子生物学分野 | 阪大 | 薬学 | 生化 twitter
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