業績|論文・出版物|目次
 

2004

Targeted adenovirus vectors

Mizuguchi H., Hayakawa T.

Hum. Gene Ther., 15, 1034-1044 (2004)

Adenovirus vector-mediated doxycycline-inducible RNA interference

Hosono T., Mizuguchi H., Katayama K., Xu ZL., Sakurai F., Ishii-Watabe A., Kawabata K., Yamaguchi T., Nakagawa S., Mayumi T., Hayakawa T.

Hum. Gene Ther., 15, 813-819 (2004)

Efficient gene transfer into human trophoblast cells with adenovirus vector containing chimeric type 5 and 35 fiber protein

Koizumi, N., Mizuguchi H., Kondoh, M., Fujii, M., Hayakawa, T., Watanabe, Y.

Biol. Pharm. Bull., 27, 2046-2048 (2004)

An improved method for detection of replication-competent retrovirus in retrovirus vector products

Uchida E., Sato K., Iwata A., Ishii-Watabe A., Mizuguchi H., Hikata M., Murata M., Yamaguchi T., Hayakawa T.

Biologicals, 32, 139-146 (2004)

High gene expression of the mutant adenovirus vector, both in vitro and in vivo, with the insertion of integrin-targeting peptide into the fiber

Gao J-Q., Inoue S., Tsukada Y., Katayama K., Eto Y., Kurachi S., Mizuguchi H., Hayakawa T., Tsutsumi Y., Mayumi T., Nakagawa S.

Pharmazie, 59, 571-572 (2004)

Simultaneous imaging of initiator/effector caspase activity and mitochondrial membrane potential during cell death in living HeLa cells

Kawai H., Suzuki T., Kobayashi T., Mizuguchi H., Hayakawa T., Kawanishi T.

Biochim. Biophys. Acta, 1693, 101-110 (2004)

Neutralizing antibody evasion ability of adenovirus vector induced by the bioconjugation of methoxypolyethylene glycol succinimidyl propionate (MPEG-SPA)

Eto Y., Gao J-Q., Sekiguchi F., Kurachi S., Katayama K., Mizuguchi H., Hayakawa T., Tsutsumi Y., Mayumi T., Nakagawa S.

Biol. Pharm. Bull., 27, 936-938 (2004)

Antibody-targeted cell fusion

Nakamura T., Peng K-W., Vongpunsawad S., Harvey M., Mizuguchi H., Hayakawa T., Cattaneo R., Russell S.J.

Nat. Biotech., 22, 331-336 (2004)

Optimization of antitumor efficacy and safety of in vivo cytokine gene therapy using RGD fiber-mutant adenovirus vector for preexisting murine melanoma

Okada Y., Okada N., Mizuguchi H., Takahashi K., Hayakawa T., Mayumi T., Mizuno N.

Biochim. Biophys. Acta, 1670, 172-180 (2004)

Anti-tumor activity of chemokine is affected by both kinds of tumors and the activation state of the host's immune system: implications for chemokine-based cancer immunotherapy

Okada N., Gao J-Q., Sasaki A., Niwa M., Okada Y., Nakayama T., Yoshie O., Mizuguchi H., Hayakawa T., Fujita T., Yamamoto A., Tsutsumi Y., Mayumi T., Nakagawa S.

Biochem. Biophys. Res. Commun., 317, 68-76 (2004)

Overexpression of constitutively activated glutamate dehydrogenase induces insulin secretion through enhanced glutamate oxidation

Anno T., Uehara S., Katagiri H., Ohta Y., Ueda K., Mizuguchi H., Moriyama Y., Oka Y., Tanizawa Y.

Am. J. Physiol., 286, E280-285 (2004)

Tumor-suppressive activities by chemokines introduced into OV-HM cells using fiber-mutant adenovirus vectors

Gao J-Q, Alexandre L.S., Tsuda Y., Katayama K., Eto Y., Sekiguchi F., Mizuguchi H., Hayakawa T., Nakayama T., Yoshie O., Tsutsumi Y., Mayumi T., Nakagawa S.

Pharmazie, 59, 238-239 (2004)

RNA interfering approach for clarifying PPARγ pathway using lentiviral vector expressing short hairpin RNA

Katayama K., Wada K., Miyoshi H., Ohashi K., Tachibana M., Furuki R., Mizuguchi H., Hayakawa T., Nakajima A., Kadowaki T., Tsutsumi Y., Nakagawa1 S., Kamisaki Y., Mayumi T.

FEBS Lett., 560, 178-182 (2004)

Dominant negative mutant of c-Jun gene transfer: a novel therapeutic strategy for colorectal cancer

Suto R., Tominaga K., Mizuguchi H., Sasaki E., Higuchi K., Kim S., Iwao H., Arakawa T.

Gene Ther., 11, 187-193 (2004)

アデノウイルスベクター

水口裕之, 早川堯夫

Mebio, メジカルビュー社, 21, 8-16 (2004)