業績｜論文・出版物｜目次｜

2001

A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the HI loop of their fiber knob

Mizuguchi H., Koizumi N., Hosono T., Utoguchi N., Watanabe Y., Kay MA., Hayakawa T.

Gene Ther., 8, 730-735 (2001)

PubMed

In vitro ligation-based cloning of foreign DNAs into the E3 and E1 deletion regions for generation of recombinant adenovirus vectors

Mizuguchi H., Kay MA., Hayakawa T.

BioTechniques, 30, 1112-1114-1116 (2001)

PubMed

Characteristics of adenovirus-mediated tetracycline-controllable expression system

Mizuguchi H., Hayakawa T.

Biochim. Biophys. Acta, 1568, 21-29 (2001)

PubMed

Efficient gene transfer by fiber-mutant adenoviral vectors containing RGD peptide

Koizumi N., Mizuguchi H., Hosono T., Ishii-Watabe A., Uchida E., Utoguchi N., Watanabe Y., Hayakawa T.

Biochim. Biophys. Acta, 1568, 13-20 (2001)

PubMed

Optimization of transcriptional regulatory elements for constructing plasmid vectors

Xu ZL., Mizuguchi H., Ishii-Watabe A., Uchida E., Mayumi T., Hayakawa T.

Gene, 272, 149-156 (2001)

PubMed

Approaches for generating recombinant adenovirus vectors

Mizuguchi H., Kay M.A., Hayakawa T.

Adv. Drug. Deli. Rev., 52, 165-176 (2001)

PubMed

Adenovirus-mediated MUC1 gene transduction into human blood-derived dendritic cells

Maruyama K., Akiyama Y., Nara-Ashizawa N., Hojo T., Cheng JY., Mizuguchi H., Hayakawa T., Yamaguchi K.

J. Immunother., 24, 345-353 (2001)

PubMed

Efficient antigen gene transduction using Arg-Gly-Asp fiber-mutant adenovirus vectors can potentiate antitumor vaccine efficacy and maturation of murine dendritic cells

Okada N., Saito T., Masunaga Y., Tsukada Y., Nakagawa S., Mizuguchi H., Mori K., Okada Y., Fujita T., Hayakawa T., Mayumi T., Yamamoto A.

Cancer Res., 61, 7913-7919 (2001)

PubMed

Efficient gene delivery into dendritic cells by fiber-mutant adenovirus vectors

Okada N., Tsukada Y., Nakagawa S., Mizuguchi H., Mori K., Saito T., Fujita T., Yamamoto A., Hayakawa T., Mayumi T.

Biochem. Biophys. Res. Commun., 282, 173-179 (2001)

PubMed

Involvement of a calcium-independent pathway in plasmin-induced platelet shape change

Ishii-Watabe A., Uchida E., Mizuguchi H., Hayakawa T.

Life Science, 69, 945-960 (2001)

PubMed

Targeting the replication of adenovirus to p53-defective thyroid carcinoma with a p53-regulated cre/loxP system

Nagayama Y., Nishihara E., Namba H., Yokoi H., Hasegawa M., Mizuguchi H., Hayakawa T., Hamada H., Yamashita S., Niwa M.

Cancer Gene Ther., 8, 36-44 (2001)

PubMed

Nuclear targeting of DNA

Nakanishi M., Akuta T., Nagoshi E., Eguchi A., Mizuguchi H., Senda T.

Eur. J. Pharm. Sci., 13, 17-24 (2001)

PubMed

Effects of erythrocytes and serum proteins on lung accumulation of lipoplexes containing cholesterol or DOPE as a helper lipid in the single-pass rat lung perfusion system

Sakurai F, Nishioka T, Yamashita F, Takakura Y, and Hashida M.

Eur. J. Pharm. Biopharm., 52, 165-172 (2001)

PubMed

Interaction between DNA-cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: the role of the neutral helper lipid

Sakurai F, Nishioka T, Saito H, Baba T, Okuda A, Matsumoto O, Taga T, Yamashita F, Takakura Y, and Hashida M.

Gene Ther., 8, 677-686 (2001)

PubMed

The earliest stages of B cell development require a chemokine stromal cell-derived factor/pre-B cell growth-stimulating factor

Egawa T, Kawabata K, Kawamoto H, Amada K, Okamoto R, Fujii N, Kishimoto T, Katsura Y, Nagasawa T.

Immunity, 15, 323-334 (2001)

PubMed

プラスミド構築に基づいた組換えアデノウイルスベクター作製技術

水口裕之, 早川堯夫

BIO INDUSTRY, シーエムシー出版, 18, 5-14 (2001)

CiNii

遺伝子治療用医薬品の実用化と一層の進展に向けて-新世代アデノウイルスベクターの開発-