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業績|論文・出版物|目次|ALL
 

Effects of cellular receptors on the vaccine efficacies of adenovirus vector-based vaccines following intramuscular and intranasal administration.

Onishi R., Shiota A., Nakatani H., Tachibana M., Shimizu K., Hirai T., Yoshioka Y., Sakurai F., Mizuguchi H.

Sci. Rep. (in press)

Efficacy of intranasal adenovirus vector vaccine is attenuated by type I IFN‒induced NK cell activation.

Nakatani M., Tachibana M., Onishi R., Nakagaki T., Ishii K.J., Shimizu K., Sakurai F., Mizuguchi H.

Mol. Ther. Adv. (in press)

ヒト肝臓オルガノイド由来肝細胞の開発と創薬応用

仝嫣然、植山(鳥羽)由希子、水口裕之

PHARM STAGE (in press)

Liver-specific suppression of PLA2G6/iPLA2β improves glucose and lipid metabolism in high-fat diet-fed mice.

Shimizu K., Nishibata M., Nagata K., Hori S., Michinaga S., Kanehara M., Hashimoto-Iwasaki M., Sakurai F., Shindou H., Tomita K., Nishinaka T., Mizuguchi H.

FASEB J., 40, e71821 (2026)

Automated high-throughput raman spectral framework for cellular differentiation monitoring.

Raj P., Li M., Ueyama-Toba Y., Mizuguchi H., Fujita K., Barman I.

Nano Lett., 26, 1357-1365 (2026)

A comparative study of CYP1A1 and CYP1A2 induction by cigarette smoke in human in vitro models.

Lenich A-K., Kishimoto W., Nakase H., Inui T., Mizuguchi H., Ruez S.

Archives of Toxicology, 100, 2009-2014 (2026)

Liver-specific overexpression of lysophospholipid acyltransferase, LPLAT10, increases glucose-stimulated insulin secretion

Shimizu K., Shindou H., Tomita K., Nishinaka T.

Seikagaku, 98, 120-125 (2026)

Oncolytic reovirus-induced prostaglandin E2 production in human tumor cells.

Ishigami I., Shimada H., Ihara A., Kawase A., Mizuguchi H., Sakurai F.

Biol. Pharm. Bull., 48, 1876-1886 (2025)

Cryopreservation of hepatocyte organoid-derived cells generated from human iPS cells.

Nagai W., Inui J., Ueyama-Toba Y., Asano R., Mizuguchi H.

Biol. Pharm. Bull., 48, 1391-1398 (2025)

Oncolytic adenovirus serotype 35 mediated tumor growth suppression via efficient activation of antitumor immunity.

Ono R., Tokuoka S., Tachibana M., Ishii J.K., Sakurai F., Mizuguchi H.

J. ImmunoTher. Cancer, 13, e006558 (2025)

Considerations for developing CYP induction assays in hepatocytes: Insights from a multilaboratory study.

Toyoda H., Nozue A., Nishida Y., Yakabe Y., Aiki Y., Ueyama-Toba Y., Takayama K., Mizuguchi H., Mori C., Torisawa Y.S., Sakai Y., Iwao T., Matsunaga T., Horiuchi S., Yamazaki D., Ishida S., Kojima N., Inamura K., Sakai Y., Nishikawa M., Mihara I., Akabane T., Ito Y.

Eur. J. Cell Biol., 104, 151497 (2025)

An in vitro safety evaluation model for assessing the effects of a chemical drug on the human intestinal barrier integrity using genetically modified Caco-2 cells expressing drug-metabolizing enzymes.

Bai L., Sakimura S., Niwa Y., Mizuguchi H., Maeda S., Ikemura K., Okuda M., Kondoh, M.

Toxicol. Lett., 410, 113-120 (2025)

Two-dimensionally cultured functional hepatocytes generated from human induced pluripotent stem cell-derived hepatic organoids for pharmaceutical research.

Inui J., Ueyama-Toba Y., Nagai W., Asano R., Mizuguchi H.

Biomaterials, 318, 123148 (2025)

Air-liquid interface culture alters the characteristics and functions of monolayers generated from human iPS cell‑derived enterocyte‑like cell organoids

Inui T., Uraya Y., Ueyama-Toba Y., Mizuguchi H.

Eur. J. Cell Biol., 104, 151479 (2025)

Evaluation of the correlation between nuclear localization levels and genome editing efficiencies of Cas12a fused with nuclear localization signals.

Tsukamoto T., Mizuta H., Sakai E., Sakurai F., Mizuguchi H.

J. Pharm. Sci., 114, 841-848 (2025)

Adenoviral Vector Construction II: Bacterial Systems

Hemmi M, Mizuguchi H.

Adenoviral Vectors for Gene Therapy (Third Edition), 131-148 (2025)

Approaches to the Treatment of Lifestyle-related Diseases Through the Regulation of Phospholipid Biosynthesis in the Liver

Shimizu K., Shindou H., Tomita K., Nishinaka T.

YAKUGAKU ZASSHI, 145, 171-176 (2025)

ヒト肝臓オルガノイドの創薬研究への応用

植山(鳥羽)由希子、仝嫣然、水口裕之

薬学雑誌, 145, 189-194 (2025)

ヒトiPS細胞を利用した生体模倣システムの構築と医薬品評価への応用

植山(鳥羽)由希子、水口裕之

薬剤学, 85, 55-59 (2025)

実験におけるクリーンベンチ・安全キャビネットの使い方

清水かほり

Drug Delivery System, 40, 77-79 (2025)

大阪大学大学院 薬学研究科 分子生物学分野 

〒565-0871 大阪府吹田市山田丘1-6 大阪大学 大学院薬学研究科・薬学部 1号館 4階

TEL: 06-6879-8185 FAX: 06-6879-8187

Copyright© Laboratory of Biochemistry and Molecular Biology, Graduate School and School of Pharmaceutical Sciences, Osaka University

directed by Prof. Hiroyuki Mizuguchi

  • 分子生物学分野 | 阪大 | 薬学 | 生化 twitter
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