業績|論文・出版物|目次|ALL
Two-dimensionally cultured functional hepatocytes generated from human induced pluripotent stem cell-derived hepatic organoids for pharmaceutical research.
Inui J., Ueyama-Toba Y., Nagai W., Asano R., Mizuguchi H.
Biomaterials (in press)
Air–liquid interface culture alters the characteristics and functions of monolayers generated from human iPS cell‑derived enterocyte‑like cell organoids
Inui T., Uraya Y., Ueyama-Toba Y., Mizuguchi H.
Eur. J. Cell Biol. (in press)
Evaluation of the correlation between nuclear localization levels and genome editing efficiencies of Cas12a fused with nuclear localization signals.
Tsukamoto T., Mizuta H., Sakai E., Sakurai F., Mizuguchi H.
J. Pharm. Sci. (in press)
Adenoviral Vector Construction II: Bacterial Systems
Hemmi M, Mizuguchi H.
Adenoviral Vectors for Gene Therapy (Third Edition) (in press)
ヒト肝臓オルガノイドの創薬研究への応用
植山(鳥羽)由希子、仝嫣然、水口裕之
薬学雑誌 (in press)
ヒト腸管オルガノイドを用いた医薬品開発プラットフォーム
乾達也、水口裕之
創薬研究における細胞培養の今 (in press)
植山(鳥羽)由希子、水口裕之
植山(鳥羽)由希子、水口裕之
薬剤学 (in press)
Small extracellular vesicles carrying reovirus, tumor antigens, interferon-β, and damage-associated molecular patterns for efficient tumor treatment
Shuwari N., Inoue C., Ishigami I., Jingushi K., Kamiya M., Kawakami S., Tsujikawa K., Tachibana M., Mizuguchi H., Sakurai F.
J Control Release, 374, 89-102 (2024)
A general fluorescence off/on strategy for fluorogenic probes: Steric repulsion-induced twisted intramolecular charge transfer (sr-TICT).
Hanaoka K., Ikeno T., Iwaki S., Deguchi S., Takayama K., Mizuguchi H., Tao F., Kojima N., Ohno H., Sasaki E., Komatsu T., Ueno T., Maeda K., Kusuhara H., Urano Y.
Sci. Adv., 10, eadi8847 (2024)
Overexpression of lysophospholipid acyltransferase, LPLAT10/LPCAT4/LPEAT2, in the mouse liver increases glucose-stimulated insulin secretion.
Shimizu K., Ono M., Mikamoto T., Urayama Y., Yoshida S., Hase T., Michinaga S., Nakanishi H., Iwasaki M., Terada T., Sakurai F., Mizuguchi H., Shindou H., Tomita K., Nishinaka T.
FASEB J., 38, e23425 (2024)
Establishment of UGT1A1-knockout human iPS-derived hepatic organoids for UGT1A1-specific kinetics and toxicity evaluation.
Shintani T.#, Imamura C.#,?Ueyama-Toba Y.,?Inui J., Watanabe A.,?Mizuguchi H. #These authors equally contributed to this work.