業績|論文・出版物|

2019

Establishment of SLC15A1/PEPT1-knockout human induced pluripotent stem cell line for intestinal drug absorption studies

Kawai K., Negoro R., Ichikawa M., Yamashita T., Deguchi S., Harada K., Hirata K., Takayama K., Mizuguchi H.
Mol. Ther. Methods Clin. Dev.
17
49-57
2019

Efficient generation of adenovirus vectors carrying the Clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR associated proteins (Cas)12a system by suppressing Cas12a expression in packaging cells

Tsukamoto T., Sakai E., Nishimae F., Sakurai F., Mizuguchi H.
J. Biotech.
304
1-9
2019

Generation of human iPS cell-derived intestinal epithelial cell monolayers by CDX2 transduction

Takayama K., Negoro R., Yamashita T., Kawai K., Ichikawa M., Mori T., Nakatsu N., Harada K., Ito S., Yamada H., Yamaura Y., Hirata K., Ishida S., Mizuguchi H.
Cell. Mol. Gastroenterol. Hepatol.
8
513-526
2019

miR-27b-mediated suppression of aquaporin-11 expression in hepatocytes reduces HCV genomic RNA levels but not viral titers

Sakurai F.#, Hashimoto R.#, Inoue C., Wakabayashi K., Tsukamoto T., Taracena-Gándara M., Imaizumi T., Sakai E., Itsuki K., Sakamoto N., Wakita T., Mizuguchi H.
Virology Journal
16
58
2019

Modeling of hepatic drug metabolism and responses in CYP2C19 poor metabolizer using genetically manipulated human iPS cells

Deguchi S., Yamashita T., Igai K., Harada K., Toba Y., Hirata K., Takayama K., Mizuguchi H.
Drug Metab. Dispos.
47
632-638
2019

FGF signal is not required for hepatoblast differentiation of human iPS cells

Toba Y., Kiso A., Nakamae S., Sakurai F., Takayama K., Mizuguchi H.
Sci. Rep.
9
3713
2019

Development of selective cytotoxic viral vectors for concentration of undifferentiated cells in cardiomyocytes derived from human induced pluripotent stem cells

Kono K., Sawada R., Kuroda T., Yasuda S., Matsuyama S., Matsuyama A., Mizuguchi H., Sato Y.
Sci. Rep.
9
3630
2019

A microRNA derived from adenovirus virus-associated RNAII promotes virus infection via post-transcriptional gene silencing

Wakabayashi K.#, Machitani M.#, Tachibana M., Sakurai F., Mizuguchi H.
J. Virol.
93
e01265-18
2019

Pharmaceutical research for inherited metabolic disorders of the liver using human induced pluripotent stem cell and genome editing technologies

Yamashita T., Takayama K., Hori M., Harada-Shiba M., Mizuguchi H.
Biol. Pharm. Bull.
42
312-318
2019

アデノウイルス由来小分子RNAによるウイルス増殖促進機構の解明と遺伝子組換えウイルスへの応用

若林圭作, 櫻井文教, 水口裕之
生産と技術
71
10-14
2019

 大阪大学大学院 薬学研究科 分子生物学分野 

〒565-0871 大阪府吹田市山田丘1-6 大阪大学 大学院薬学研究科・薬学部 1号館 4階

TEL: 06-6879-8185 FAX: 06-6879-8187

 

Copyright© Laboratory of Biochemistry and Molecular Biology, Graduate School and School of Pharmaceutical Sciences, Osaka University

directed by Prof. Hiroyuki Mizuguchi

  • 分子生物学分野 | 阪大 | 薬学 | 生化 twitter