業績|論文・出版物|

2018

Systemically administered reovirus-induced down-regulation of hypoxia inducible factor-1α in subcutaneous tumors

Hotani T., Mizuguchi H., Sakurai F.
Mol. Ther. Oncolytics
12
162-172
2018

Efficient generation of small intestinal epithelial-like cells from human iPS cells for drug absorption and metabolism studies

Negoro R., Takayama K., Kawai K., Harada K., Sakurai F., Hirata K., Mizuguchi H.
Stem Cell Rep.
11
1539-1550
2018

Optimal human iPS cell culture method for efficient hepatic differentiation

Matoba N.#, Yamashita T.#, Takayama K., Sakurai F., Mizuguchi H.
Differentiation
104
13-21
2018

LY341495, an mGluR2/3 antagonist, regulates the immunosuppressive function of myeloid-derived suppressor cells and inhibits melanoma tumor growth

Morikawa N., Tachibana M., Ago Y., Goda H., Sakurai F., Mizuguchi H.
Biol. Pharm. Bull.
41
1866-1869
2018

Antibodies against adenovirus fiber and penton base proteins inhibit adenovirus vector-mediated transduction in the liver following systemic administration

Tomita K., Sakurai F., Iizuka S., Hemmi M., Wakabayashi K., Tachibana M., Katayama K., Kamada H., Mizuguchi H.
Sci. Rep.
8
12315
2018

Generation of the adenovirus vector-mediated CRISPR/Cpf1 system and the application for primary human hepatocytes prepared from humanized mice with chimeric liver

Tsukamoto T., Sakai E., Iizuka S., Taracena-Gándara M., Sakurai F., Mizuguchi H.
Biol. Pharm. Bull.
41
1089-1095
2018

Enrichment of high-functioning human iPS cell-derived hepatocyte-like cells for pharmaceutical research

Takayama K., Hagihara Y., Toba Y., Sekiguchi K., Sakurai F., Mizuguchi H.
Biomaterials
161
24-32
2018

Oncolytic reovirus inhibits immunosuppressive activity of myeloid-derived suppressor cells in a TLR3-dependent manner

Katayama Y., Tachibana M., Kurisu N., Oya Y., Terasawa Y., Goda H., Kobiyama K., Ishii K., Akira S., Mizuguchi H., Sakurai F.
J. Immunol.
200
2987-2999
2018

Nanaomycin A treatment promotes hepatoblast differentiation from human iPS cells

Nakamae S.#, Toba Y.#, Takayama K., Sakurai F., Mizuguchi H.
Stem Cells Dev.
27
405-414
2018

Billion-scale production of hepatocyte-like cells from human iPS cells

Yamashita T., Takayama K., Sakurai F., Mizuguchi H.
Biochem. Biophys. Res. Commun.
496
1269–1275
2018

Occludin as a functional marker of vascular endothelial cells on tube-forming activity

Kanayasu-Toyoda T., Ishii-Watabe A., Kikuchi Y., Kitagawa H., Suzuki H., Tamura H., Tada M., Suzuki T., Mizuguchi H., Yamaguchi T.
J. Cell. Physiol.
233
1700-1711
2018

Generation of optogenetically modified adenovirus vector for spatiotemporally controllable gene therapy

Takayama K., Mizuguchi H.
ACS Chem. Biol.
13
449–454
2018

Detection of CTCs in cervical cancer using a conditionally replicative adenovirus targeting telomerase-positive cells

Takakura M., Matsumoto T., Nakamura M., Mizumoto Y., Myojyo S., Yamazaki R., Iwadare J., Bono Y., Orisaka S., Obata T., Izuka T., Kagami K., Nakayama K., Hayakawa H., Sakurai F., Mizuguchi H., Urata Y., Fujiwara T., Kyo S., Sasagawa T., Fujiwara H.
Cancer Sci.
109
231-240
2018

Human iPS cell-based liver-like tissue engineering at extrahepatic sites in mice as a new cell therapy for hemophilia B

Okamoto R.#, Takayama K.#, Akita N.#, Nagamoto Y., Hosokawa D., Iizuka S., Sakurai F., Suemizu H., Ohashi K., Mizuguchi H.
Cell Transplant.
27
299-309
2018

アデノウイルスベクター

水口裕之, 早川堯夫
バイオロジクスの開発と品質・安全性確保
2018

組換えアデノウイルス ―特性と最近の話題―

水口裕之, 邊見昌久
医学のあゆみ
351-358
2018

粘膜免疫誘導型ワクチンとしてのアデノウイルスベクター

立花雅史, 邊見昌久, 水口裕之
ドラッグデリバリーシステム
2018

ヒトiPS細胞由来肝細胞の創出と創薬研究への応用

三谷成二, 高山和雄, 水口裕之
PHARM STAGE
2018

 大阪大学大学院 薬学研究科 分子生物学分野 

〒565-0871 大阪府吹田市山田丘1-6 大阪大学 大学院薬学研究科・薬学部 1号館 4階

TEL: 06-6879-8185 FAX: 06-6879-8187

 

Copyright© Laboratory of Biochemistry and Molecular Biology, Graduate School and School of Pharmaceutical Sciences, Osaka University

directed by Prof. Hiroyuki Mizuguchi

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