業績|論文・出版物|

2016

Transplantation of a human iPSC-derived hepatocyte sheet increases survival in mice with acute liver failure

Nagamoto Y., Takayama K., Ohashi K., Okamoto R., Sakurai F., Tachibana M., Kawabata K., Mizuguchi H.
J. Hepatol.
64
1068-1075
2016

NF-kB promotes leaky expression of adenovirus genes in a replication-incompetent adenovirus vector

Machitani M.#, Sakurai F.#, Wakabayashi K., Nakatani K., Shimizu K., Tachibana M., Mizuguchi H.
Sci. Rep.
6
19922
2016

Efficient detection of human circulating tumor cells without significant production of false-positive cells by a novel conditionally replicating adenovirus

Sakurai F., Narii N., Tomita K., Togo S., Takahashi K., Machitani M., Tachibana M., Ouchi M., Katagiri N., Urata Y., Fujiwara T., Mizuguchi H.
Mol. Ther. Methods Clin. Dev.
3
16001
2016

Dicer functions as an antiviral system against human adenoviruses via cleavage of adenovirus-encoded noncoding RNA

Machitani M.#, Sakurai F.#, Wakabayashi K., Tomita K., Tachibana M., Mizuguchi H.
Sci. Rep.
6
27598
2016

Laminin 411 and 511 promote the cholangiocyte differentiation of human induced pluripotent stem cells

Takayama K.#, Mitani S.#, Nagamoto Y., Sakurai F., Tachibana M., Taniguchi Y., Sakaguchi K., Mizuguchi H.
Biochem. Biophys. Res. Commun.
474
91-96
2016

Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells

Negoro R.#, Takayama K.#, Nagamoto Y., Sakurai F., Tachibana M., Mizuguchi H.
Biochem. Biophys. Res. Commun.
472
631-636
2016

Hepatic maturation of human iPS cell-derived hepatocyte-like cells by ATF5, c/EBPα, and PROX1 transduction

Nakamori D.#, Takayama K.#, Nagamoto Y., Mitani S., Sakurai F., Tachibana M., Mizuguchi H.
Biochem. Biophys. Res. Commun.
469
424-429
2016

TANK-binding kinase 1-dependent or -independent signaling elicits the cell type-specific innate immune responses induced by the adenovirus vector

Tsuzuki S.#, Tachibana M.#, Hemmi M., Yamaguchi T., Shoji M., Sakurai F., Kobiyama K., Kawabata K., Ishii K.J., Akira S., Mizuguchi H.
Int. Immunol.
28
105-115
2016

Adenovirus vector-based incorporation of a photo-cross-linkable amino acid into proteins in human primary cells and cancerous cell lines

Kita A., Hino N., Higashi S., Hirota K., Narumi R., Adachi J., Takafuji K., Ishimoto K., Okada Y., Sakamoto K., Tomonaga T., Takashima S., Mizuguchi H., Doi T.
Sci. Rep.
6
36946
2016

Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells

Yanagihara K., Liu Y., Kanie K., Takayama K., Kokunugi M., Hirata M., Fukuda T., Suga M., Nikawa H., Mizuguchi H., Kato R., Furue M.K.
Stem Cells Dev.
25
1884-1897
2016

Coating with Spermine-Pullulan Polymer Enhances Adenoviral Transduction of Mesenchymal Stem Cells

Wan L., Yao X., Faiola F., Liu B., Zhang T., Tabata Y., Mizuguchi H., Nakagawa S., Gao J.Q, Zhao R.C.
Int. J. Nanomed.
11
6763-6769
2016

Tumor-specific delivery of biologics by a novel T-cell line HOZOT

Onishi T., Tazawa H., Hashimoto Y., Takeuchi M., Otani T., Nakamura S., Sakurai F., Mizuguchi H., Kishimoto H., Umeda Y., Shirakawa Y., Urata Y., Kagawa S., Fujiwara T.
Sci. Rep.
6
38060
2016

Expression of HIF-1α ODD domain fused canine caspase 3 by EGFR promoter-driven adenovirus vector induces cytotoxicity in canine breast tumor cells under hypoxia

Okamoto M., Asamura A., Tanaka K., Soeda T., Watanabe K., Mizuguchi H., Ikeda T.
Vet. Res. Commun.
40
131-139
2016

Targeted photodynamic virotherapy armed with a genetically encoded photosensitizer

Takehara K., Tazawa H., Okada N., Hashimoto Y., Kikuchi S., Kuroda S., Kishimoto H., Shirakawa Y., Narii N., Mizuguchi H., Urata Y., Kagawa S., Fujiwara T.
Mol. Cancer Ther.
15
199-208
2016

Adenoviral Vector Construction II: Bacterial Systems

Hemmi M., Mizuguchi H.
Adenoviral Vectors for Gene Therapy (Second Edition)
113-137
2016

ヒトiPS細胞から肝細胞への分化誘導と毒性評価系への応用

水口裕之, 高山和雄
SCAS NEWS 2016-Ⅱ
3-7
2016

ヒトiPS細胞を用いた薬剤評価のための肝細胞の作製

水口裕之, 高山和雄
iPS細胞の安全・高品質な作製技術
124-130
2016

薬物毒性評価

水口裕之, 高山和雄
臨床薬学テキストシリーズ
233-239
2016

標的化アデノウイルスベクターの開発

町谷充洋, 水口裕之
遺伝子医学MOOK 30 今、着実に実り始めた遺伝子治療~最新研究と今後の展望
63-73
2016