業績|論文・出版物|

2010

Adenovirus vector covalently conjugated to polyethylene glycol with a cancer-specific promoter suppresses the tumor growth through systemic administration

Yao X., Yoshioka Y., Morishige T., Eto Y., Narimatsu S., Mizuguchi H., Mukai Y., Okada N., Nakagawa S.
Biol. Pharm. Bull.
35
1073-1076
2010

マイクロRNAによる遺伝子発現制御システムを搭載した遺伝子組換えアデノウイルスの開発

櫻井文教, 水口裕之
薬学雑誌
130
1497-1504
2010

iPS細胞への遺伝子導入を用いた分化誘導の最適化

川端健二, 田代克久, 水口裕之
薬学雑誌
130
1527-1534
2010

次世代アデノウイルスベクターの開発と生命科学研究への応用

水口裕之
Drug Delivery System
25
493-503
2010

Adenovirus serotype 35 vector-induced innate immune responses in dendritic cells derived from wild-type and human CD46-transgenic mice: Comparison with a fiber-substituted Ad vector containing fiber proteins of Ad serotype 35

Sakurai, F., Nakashima, K., Yamaguchi, T., Ichinose, T., Kawabata, K., Hayakawa, T., and Mizuguchi, H.
J. Control. Release
148
212-218
2010

Induction of type I interferon by adenovirus-encoded small RNAs

Yamaguchi T., Kawabata K., Kouyama E., Ishii K.J., Katayama K., Suzuki T., Kurachi S., Sakurai F., Akira S., Mizuguchi H.
Proc. Natl. Acad. Sci. USA
107
17286-17291
2010

Adenovirus vector-mediated efficient transduction into human embryonic and induced pluripotent stem cells

Tashiro K., Kawabata K., Inamura M., Takayama K., Furukawa N., Sakurai F., Katayama K., Hayakawa H., Furue-Kusuda M., Mizuguchi H.
Cell. Reprogram.
12
501-507
2010

Optimized PEGylated adenovirus vector reduces the anti-vector humoral immune response against adenovirus and induces a therapeutic effect against metastatic lung cancer

Eto Y., Yoshioka Y., Ishida T., Yao X., Morishige T., Narimatsu S., Mizuguchi H., Mukai Y., Okada N., Kiwada H., Nakagawa S.
Biol. Pharm. Bull.
33
1540-1544
2010

Prevention of hepatic ischemia-reperfusion injury by pre-administration of catalase-expressing adenovirus vectors

Ushitora M., Sakurai F., Yamaguchi T., Nakamura S-I., Kondoh M., Yagi K., Kawabata K., Mizuguchi H.
J. Control. Release
142
431-437
2010

A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy

Watanabe Y., Kojima T., Kagawa S., Uno F., Hashimoto Y., Kyo S., Mizuguchi H., Tanaka N., Kawamura H., Ichimaru D., Urata Y., Fujiwara T.
Oncogene
29
1145-1154
2010

A fiber modified adenovirus vector that targets to the EphrinA2 receptor reveals enhanced gene transfer to ex vivo pancreatic cancer

Van Geer M.A., Brevoord D., Kuhlmann K.F., Bakker C.T., Mizuguchi H., Wesseling J.G., Ten Kate F.J., Gouma D.J., Oude Elferink R.P., Bosma P.J.
Int. J. Oncol.
36
233-44
2010

Comparison of the anti-tumor activity of native, secreted, and membrane-bound LIGHT in mouse tumor models

Morishige T., Yoshioka Y., Tanabe A., Yao X., Mizuguchi H., Tsunoda S., Tsutsumi Y., Mukai Y., Okada N., Nakagawa S.
Int. Immunopharmacol.
10
26-33
2010

In vivo biological purging for lymph node metastasis of human colorectal cancer by telomerase-specific oncolytic virotherapy

Kojima T., Watanabe Y., Hashimoto Y., Kuroda S., Yamasaki Y., Yano S., Ouchi M., Tazawa H., Uno F., Kagawa S., Kyo S., Mizuguchi H., Urata Y., Tanaka N., Fujiwara T.
Ann. Surg.
251
1079-1086
2010

Particle tracking of intracellular trafficking of octaarginine-modified liposomes: a comparative study with adenovirus

Akita H., Enoto K., Masuda T., Mizuguchi H., Tani T., Harashima H.
Mol. Ther.
18
955-964
2010

Co-administration of viral vector-based vaccines suppresses antigen-specific effector CD8 T cells

Yashima S., Yoshizaki S., Shinoda K., Yoshida A., Kondo A., Mizuguchi H., Ryo A., Okuda K., Shimada M.
Vaccine
28
3257-3264
2010

Claudin-4-targeting of diphtheria toxin fragment A using a C-terminal fragment of Clostridium perfringens enterotoxin

Kakutani H., Kondoh M., Saeki R., Fujii M., Watanabe Y., Mizuguchi H., Yagi K.
Eur. J. Pharm. Biopharm.
75
213-217
2010

 大阪大学大学院 薬学研究科 分子生物学分野 

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TEL: 06-6879-8185 FAX: 06-6879-8187

 

Copyright© Laboratory of Biochemistry and Molecular Biology, Graduate School and School of Pharmaceutical Sciences, Osaka University

directed by Prof. Hiroyuki Mizuguchi

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