業績|論文・出版物|

2009

Development of fiber-substituted adenovirus vectors containing foreign peptides in the adenovirus serotype 35 fiber knob

Matsui H., Sakurai F., Kurachi S., Tashiro K., Sugio K., Kawabata K., Yamanishi K., Mizuguchi H.
Gene Ther.
16
1050-1057
2009

Efficient adipocyte and osteoblast differentiation from mouse induced pluripotent stem cells by adenoviral transduction

Tashiro K., Inamura M., Kawabata K., Sakurai F., Yamanishi K., Hayakawa T., Mizuguchi H.
Stem Cells
27
102-1811
2009

Systemic administration of a PEGylated adenovirus vector with a cancer-specific promoter is effective in a mouse model of metastasis

Yao X., Yoshioka Y., Morishige T., Eto Y., Watanabe H., Okada Y., Mizuguchi H., Mukai Y., Okada N., Nakagawa S.
Gene Ther.
16
1395-404
2009

A simple biological imaging system for detecting viable human circulating tumor cells

Kojima T., Hashimoto Y., Watanabe Y., Kagawa S., Uno F., Kuroda S., Tazawa H., Kyo S., Mizuguchi H., Urata Y., Tanaka N., Fujiwara T.
J. Clin. Invest.
119
3172-3181
2009

Intratracheal delivery of CX3CL1-expressing mesenchymal stem cells to multiple lung tumors

Xin H., Sun R., Kanehira M., Takahata T., Itoh J., Mizuguchi H., Saijo Y.
Mol. Med.
15
321-327
2009

Improved gene transfer into renal carcinoma cells using adenovirus vector containing RGD motif

Terao S., Acharya B., Suzuki T., Aoi T., Naoe M., Hamada K., Mizuguchi H., Gotoh A.
Anticancer Res.
29
2997-3001
2009

Transduction of adenovirus vectors modified with cell penetrating peptides

Eto Y., Yoshioka Y., Asavatanabodee R., Kida S., Maeda M., Mukai Y., Mizuguchi H., Kawasaki K., Okada N., Nakagawa S.
Peptides
30
1548-1552
2009

Ephrin A2 receptor targeting does not increase adenoviral pancreatic cancer transduction in vivo

Van Geer M.A., Bakker C.T., Koizumi N., Mizuguchi H., Wesseling J.G., Oude Elferink R.P.J., Bosma P.J.
World J. Gastroenterol.
15
2754-2762
2009

Telomerase-Specific Virotheranostics for Human Head and Neck Cancer

Kurihara Y., Watanabe Y., Onimatsu H., Kojima T., Shirota T., Hatori M., Liu D., Kyo S., Mizuguchi H., Urata Y., Shintani S., Fujiwara T.
Clin. Cancer Res.
15
2335-2343
2009

Adenovirus serotype 35 vector-mediated transduction following direct administration into organs of nonhuman primates

Sakurai F., Nakamura S-I., Akitomo K., Shibata H., Terao K., Kawabata K., Hayakawa T., Mizuguchi H.
Gene Ther.
16
297-302
2009

Efficient osteoblast differentiation from mouse bone marrow stromal cells with polylysin-modified adenovirus vectors

Tashiro K., Kondo A., Kawabata K., Sakurai H., Sakurai F., Yamanishi K., Hayakawa T., Mizuguchi H.
Biochem. Biophys. Res. Commun.
379
127-132
2009

Designed recombinant adenovirus type 5 vector induced env-specific CD8+ cytotoxic T lymphocytes and cross-reactive neutralizing antibodies against human immunodeficiency virus type 1

Ura T., Yoshida A., Xin K-Q., Yoshizaki S., Yashima S., Abe S, Mizuguchi H., Okuda K.
J. Gene Med.
11
139-149
2009

Adenovirus type 5 with modified hexons induces robust transgene-specific immune responses in mice with pre-existing immunity against adenovirus type 5

Abe S., Okuda K., Ura T., Kondo A., Yoshida A., Yoshizaki S., Mizuguchi H., Klinman D., Shimada M.
J. Gene Med.
11
570-579
2009

Suppressive effects of sugar-modified cationic liposome/NF-κB decoy complexes on adenovirus vector-induced innate immune responses

Huang H., Sakurai F., Higuchi Y., Kawakami S., Hashida M., Kawabata K., Hayakawa T., Mizuguchi H.
J. Control. Release
133
139-145
2009

NK cells are migrated and indispensable in the anti-tumor activity induced by CCL27 gene therapy

Gao J-Q., Tsuda Y., Han M., Xu D-H., Kanagawa N., Hatanaka Y., Tani Y., Mizuguchi H., Tsutsumi Y., Mayumi T., Okada N., Nakagawa S.
Cancer Immunol. Immunother.
58
291-299
2009

Effect of therapeutic immunization using Ad5/35 and MVA vectors on SIV-infection of rhesus monkeys undergoing anti-retroviral therapy

Shimada M, Wang H-B., Ino A., Xu X-P., Yoshida A., Shinoda K., Ura T., Mizuguchi H., Klinman D., Luo J-L., Bai H., Okuda K.
Gene Ther.
16
218-228
2009

改良型アデノウイルスベクター開発の最前線

水口裕之
脳21
12
123-131
2009

アデノウイルスベクターの作製・増幅・精製法

水口裕之
脳21
12
246-251
2009

iPS細胞を活用した安全性・有効性評価系の構築

古江-楠田美保, 山田弘, 水口裕之
iPS細胞の産業的応用技術
218~224
2009

アデノウイルスベクターのDDS

水口裕之, 櫻井文教, 川端健二
Pharm Tech Japan
25
2618-2624
2009

ゲノム解析と遺伝子DDSの設計・評価

水口裕之
Pharm Tech Japan
25(13)
2009

組換えウイルスキャリア-遺伝子治療・ワクチン応用への新展開-

水口裕之
Drug Delivery System
24
569
2009

遺伝子組換えウイルスの安全性向上に向けた遺伝子改変~microRNAによる遺伝子発現制御システムを搭載した組換えウイルスの開発~

櫻井文教, 川端健二, 水口裕之
Drug Delivery System
24
572-581
2009

 大阪大学大学院 薬学研究科 分子生物学分野 

〒565-0871 大阪府吹田市山田丘1-6 大阪大学 大学院薬学研究科・薬学部 1号館 4階

TEL: 06-6879-8185 FAX: 06-6879-8187

 

Copyright© Laboratory of Biochemistry and Molecular Biology, Graduate School and School of Pharmaceutical Sciences, Osaka University

directed by Prof. Hiroyuki Mizuguchi

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