業績|論文・出版物|

2008

miR-122a-regulated expression of a suicide gene prevents hepatotoxicity without altering antitumor effects in suicide gene therapy

Suzuki T., Sakurai F., Nakamura S-I., Kouyama E., Kawabata K., kondoh M., Yagi K., Mizuguchi H.
Mol. Ther.
16
1719-1726
2008

Adenoviral expression of suppressor of cytokine signaling-1 reduces adenovirus vector-induced innate immune response

Sakurai H., Tashiro K., Kawabata K., Yamaguchi T., Sakurai F., Nakagawa S., Mizuguchi H.
J. Immunol.
180
4931-4938
2008

Transduction properties of adenovirus serotype 35 vectors after intravenous administration into nonhuman primates

Sakurai F., Nakamura S-I., Akitomo K., Shibata H., Terao K., Kawabata K., Hayakawa T., Mizuguchi H.
Mol. Ther.
16
726-733
2008

Efficient adenovirus vector-mediated PPAR gamma gene transfer into mouse embryoid bodies promotes adipocyte differentiation, J

Tashiro K., Kawabata K., Sakurai H., Kurachi S., Sakurai F., Yamanishi K., Mizuguchi H.
Gene Med.
10
498-507
2008

Efficient gene delivery in human and rodent mast cells using adenovirus vectors

Nakashima K., Sakurai F., Kawabata K., Mizuguchi H.
J. Control. Release
129
215-222
2008

Innate immune response induced by gene delivery vectors

Sakurai H., Kawabata K., Sakurai F., Nakagawa S., Mizuguchi H.
Int. J. Pharm.
354
9-15
2008

Modification of pIX or hexon based on fiberless Ad vectors is not effective for targeted Ad vectors

Kurachi S., Koizumi N., Tashiro K., Sakurai H., Sakurai F., Kawabata K., Nakagawa S., Mizuguchi H.
J. Control. Release
127
88-95
2008

Engineering of highly immunogenic long-lived DC vaccines by antiapoptotic protein gene transfer to enhance cancer vaccine potency

Yoshikawa T., Niwa T., Okada N., Mizuguchi H., Nakagawa S.
Gene Ther.
15
1321-1329
2008

Combination of two fiber-mutant adenovirus vectors, one encoding the chemokine FKN and another encoding cytokine interleukin 12, elicits notably enhanced anti-tumor responses

Gao J-Q., Kanagawa N., Xu D-H., Han M., Sugita T., Hatanaka Y., Tani Y., Mizuguchi H., Tsutsumi Y., Mayumi T., Okada N., Nakagawa S.
Cancer Immunol. Immunother.
57
1657-64
2008

Evaluation of promoter strength in mouse and rat primary hepatocytes using adenovirus vectors

Arita E., Kondoh M., Isoda K., Nishimori H., Yoshida T., Mizuguchi H., Yagi K.
Eur. J. Pharm. Biopharm.
70
1-6
2008

Domain mapping of a claudin-4 modulator, the C-terminal region of C-terminal fragment of Clostridium perfringens enterotoxin, by site-directed mutagenesis

Takahashi A., Komiya E., Kakutani H., Yoshida T., Fujii M., Horiguchi Y., Mizuguchi H., Tsutsumi Y., Tsunoda S-I., Koizumi N., Isoda K., Yagi K., Watanabe Y., Kondoh M.
Biochem. Pharmacol.
75
1639-1648
2008

Factors involved in the maturation of murine dendritic cells transduced with adenoviral vector variants

Kanagawa N., Koretomo R., Murakami S., Sakurai F., Mizuguchi H., Nakagawa S., Fujita T., Yamamoto A., Okada N.
Virology
374
411-420
2008

Tat conjugation of adenovirus vector broadens tropism and enhances transduction efficiency

Yoshioka Y., Asavatanabodee R., Eto Y., Watanabe H., Morishige T., Yao X., Kida S., Maeda M., Mukai Y., Mizuguchi H., Kawasaki K., Okada N., Nakagawa S.
Life Science
83
747-755
2008

Downregulation of CD46 during muscle differentiation: implications for gene transfer to human skeletal muscle using group B adenoviruses

Larochelle N., Deol J., Srivastava V., Allen C., Mizuguchi H., Karpati G., Holland P., Nalbantoglu J.
Hum. Gene Ther.
19
133-142
2008

Development and evaluation of a novel gene delivery vehicle composed of adenovirus serotype 35

Sakurai F.
Biol. Pharm. Bull.
31
1819-1825
2008

Development of a replication-incompetent adenovirus vector derived from subgroup B adenovirus serotype 35

Sakurai F.
Yakugaku Zasshi
128
1751-1761
2008

標的指向性を有するバイオコンジュゲート化アデノウイルスベクターの開発

衛藤佑介, 吉岡靖雄, Asavatanabodee R, 水口裕之, 向洋平, 岡田直貴, 中川晋作
薬学雑誌
128
1733-1742
2008

遺伝子治療研究の動向

水口裕之
医薬ジャーナル新薬展望2008
44
235-242
2008

ウイルスベクター

水口裕之
ウイルスハンドブック
6-7
2008

アデノウイルスベクター

水口裕之
機能性DDSキャリアの製剤設計
133-141
2008

 大阪大学大学院 薬学研究科 分子生物学分野 

〒565-0871 大阪府吹田市山田丘1-6 大阪大学 大学院薬学研究科・薬学部 1号館 4階

TEL: 06-6879-8185 FAX: 06-6879-8187

 

Copyright© Laboratory of Biochemistry and Molecular Biology, Graduate School and School of Pharmaceutical Sciences, Osaka University

directed by Prof. Hiroyuki Mizuguchi

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