業績|論文・出版物|

2007

Comparison of gene expression efficiency and innate immune response induced by Ad vector and lipoplex

Sakurai H., Sakurai F., Kawabata K., Sasaki T., Koizumi N., Huang H., Tashiro K., Kurachi S., Nakagawa S., Mizuguchi H.
J. Control. Release
117
430-437
2007

Role of tyrosine residues in modulation of claudin-4 by the C-terminal fragment of Clostridium perfringens enterotoxin

Harada M., Kondoh M., Ebihara C., Takahashi A., Komiya E., Fujii M., Mizuguchi H., Tsunoda S-I., Horiguchi Y., Yagi K., Watanabe Y.
Biochem. Pharmacol.
73
206-214
2007

Role of Tyr306 in the C-terminal fragment of Clostridium perfringens enterotoxin for modulation of tight junction

Ebihara C., Kondoh M., Harada M., Fujii M., Mizuguchi H., Tsunoda S-I., Horiguchi Y., Yagi K., Watanabe Y.
Biochem. Pharmacol.
73
824-830
2007

Quantitative and mechanism-based investigation of post-nuclear delivery events between adenovirus and lipoplex

Hama S., Akita H., Iida S., Mizuguchi H., Harashima H.
Nuc. Acid Res.
35
1533-1543
2007

Induction of human adiponectin gene transcription by telmisartan, angiotensin receptor blocker, independently on PPAR-gamma activation

Moriuchi A., Yamasaki H., Shimamura M., Kita A., Kuwahara H., Fujishima K., Satoh T., Fukushima K., Fukushima T., Hayakawa T., Mizuguchi H., Nagayama Y., Abiru N., Kawasaki E., Eguchi K.
Biochem. Biophys. Res. Commun.
356
1024-1030
2007

Efficient gene transfer into murine pancreatic islets using adenovirus vectors

Mukai E., Fujimoto S., Sakurai F., Kawabata K., Yamashita M., Inagaki N., Mizuguchi H.
J. Control. Release
119
136-141
2007

Downregulation of human CD46 by adenovirus serotype 35 vectors

Sakurai F., Akitomo K., Kawabata K., Hayakawa T., Mizuguchi H.
Gene Ther.
14
912-919
2007

Chimeric adenovirus 5/35 vector containing the clade C HIV gag gene induces a cross-reactive immune response against HIV

Xin K-Q., Sekimoto Y., Takahashi T., Mizuguchi H., Ichino M., Yoshida A., Okuda K.
Vaccine
25
3809-3815
2007

Cotransduction of CCL27 gene can improve the efficacy and safety of IL-12 gene therapy for cancer

Gao J-Q., Kanagawa N., Motomura Y., Yanagawa T., Sugita T., Hatanaka Y., Tani Y., Mizuguchi H., Tsutsumi Y., Mayumi T., Okada N., Nakagawa S.
Gene Ther.
14
491-502
2007

Expression of coxsackie and adenovirus receptor reduces the lung metastatic potential of murine tumor cells

Yamashita M., Ino A., Kawabata K., Sakurai F., Mizuguchi H.
Int. J. Cancer
121
1690-1696
2007

Fiber-modified adenovirus vectors containing the TAT peptide derived from human immunodeficiency virus in the fiber knob have efficient gene transfer activity

Kurachi S., Tashiro K., Sakurai F., Sakurai H., Kawabata K., Yayama K., Okamoto H., Nakagawa S., Hayakawa T., Mizuguchi H.
Gene Ther.
14
1160-1165
2007

Positive and negative regulation of adenovirus infection by CAR-like soluble protein, CLSP

Kawabata K., Tashiro K., Sakurai F., Osada N., Kusuda J., Hayakawa T., Yamanishi K., Mizuguchi H.
Gene Ther.
14
1199-1207
2007

Role of MyD88 and TLR9 in the innate immune response elicited by serotype 5 adenoviral vectors

Yamaguchi T.#, Kawabata K.#, Koizumi N., Sakurai F., Nakashima K., Sasaki T., Okada N, Mizuguchi H.
Hum. Gene Ther.
18
753-762
2007

Targeted-delivery of CX3CL1 to multiple lung tumors by mesenchymal stem cells

Xin H., Kanehira M., Mizuguchi H., Hayakawa T., Kikuchi T., Nukiwa T., Saijo Y.
Stem Cells
25
1618-1626
2007

Adenovirus vectors composed of subgroup B adenoviruses

Sakurai F., Kawabata K., Mizuguchi H.
Curr. Gene Ther.
7
229-238
2007

Chimeric adenovirus type 5/35 vector encoding SIV gag and HIV env genes affords protective immunity against the simian/human immunodeficiency virus in monkeys

Someya K., Xin K-Q., Ami Y., Izumi Y., Mizuguchi H., Ohta S., Yamamoto N., Honda M., Okuda K.
Virology
367
390-397
2007

Effective tumor targeted gene transfer using PEGylated adenovirus vector via systemic administration

Gao J-Q., Eto Y., Yoshioka Y., Sekiguchi F, Kurachi S., Morishige T., Yao X., Watanabe H., Asavatanabodee R., Sakurai F., Mizuguchi H., Okada Y., Mukai Y., Tsutsumi Y., Mayumi T., Okada N., Nakagawa S.
J. Control. Release
122
102-110
2007

Interaction of penton base Arg-Gly-Asp motifs with integrins is crucial for adenovirus serotype 35 vector transduction in human hematopoietic cells

Murakami S.#, Sakurai F.#, Kawabata K., Okada N., Fujita T., Yamamoto A., Hayakawa T., Mizuguchi H.
Gene Ther.
14
1525-1533
2007

TERT promoter-driven adenovirus vector for cancer gene therapy via systemic injection

Yao X., Yoshioka Y., Eto Y., Morishige T., Okada Y., Mizuguchi H., Mukai Y., Okada N., Nakagawa S.
Biochem. Biophys. Res. Commun.
362
419-424
2007

Targeted delivery of NK4 to multiple lung tumors by bone marrow-derived mesenchymal stem cells

Kanehira M., Xin H., Hoshino K., Maemondo M., Mizuguchi H., Hayakawa T., Matsumoto K., Nakamura T., Nukiwa T., Saijo Y.
Cancer Gene Ther.
14
894-903
2007

Role of a novel protein, CAR-like soluble protein (CLSP), in adenovirus infection

Kawabata K.
Yakugaku Zasshi
127
1091-1096
2007

アデノウイルスベクター開発の最前線

水口裕之
バイオテクノロジージャーナル
7
168-173
2007

改良型アデノウイルスベクターを用いた各種幹細胞への遺伝子デリバリー

川端健二, 櫻井文教, 水口裕之
Drug Delivery System
22
148-154
2007

各種幹細胞への高効率遺伝子導入法の開発とその応用

川端健二
Drug Delivery System
22
668-669
2007

アデノウイルスベクター

水口裕之, 早川堯夫
バイオ医薬品の開発と品質・安全性確保
563-577
2007

遺伝子治療用医薬品の品質,安全性等の確保

早川堯夫, 前田大輔, 水口裕之
バイオ医薬品の開発と品質・安全性確保
551-562
2007

遺伝子導入技術開発とその応用

水口裕之
大阪医薬品協会会報
699
21-45
2007

カプシドタンパク質改変アデノウイルスベクター

水口裕之, 櫻井文教, 川端健二
遺伝子医学MOOK別冊 絵で見てわかるナノDDS
235-242
2007

Fiber-modified adenovirus vectors decrease liver toxicity through reduced interleukin 6 production

Koizumi N., Yamaguchi T., Kawabata K., Sakurai F., Sasaki T., Watanabe Y., Hayakawa T., Mizuguchi H.
J. Immunol.
178
1767-1773
2007

Characterization of capsid-modified adenovirus vectors containing heterologous peptides in the fiber knob, protein IX, or hexon

Kurachi S., Koizumi N., Sakurai F., Kawabata K., Sakurai H., Nakagawa S., Hayakawa T., Mizuguchi H.
Gene Ther.
14
266-274
2007

Rapid construction of small interfering RNA-expressing adenovirus vectors on the basis of direct cloning of short hairpin RNA-coding DNAs

Mizuguchi H., Funakoshi N., Hosono T., Sakurai F., Kawabata K., Yamaguchi T., Hayakawa T.
Hum. Gene Ther.
18
74-80
2007