業績|論文・出版物|

2006

創薬・創剤人

櫻井文教, 川端健二
Pharm Tech Japan
22
18-19
2006

Modified adenoviral vectors ablated for coxsackievirus-adenovirus receptor, αv integrin, and heparan sulfate binding reduce in vivo tissue transduction and toxicity

Koizumi N., Kawabata K., Sakurai F., Watanebe Y., Hayakawa T., Mizuguchi H.
Hum. Gene Ther.
17
264-279
2006

Adenovirus serotype 35 vector-mediated transduction into human CD46-transgenic mice

Sakurai F., Kawabata K., Koizumi N., Inoue N., Okabe M., Yamaguchi T., Hayakawa T., Mizuguchi H.
Gene Ther.
13
1118-1126
2006

The short consensus repeats 1 and 2, not the cytoplasmic domain, of human CD46 are crucial for infection of subgroup B adenovirus serotype 35

Sakurai F., Murakami S., Kawabata K., Okada N., Yamamoto A., Seya T., Hayakawa T., Mizuguchi H.
J. Control. Release
113
271-278
2006

Adenovirus vector-mediated gene transfer into stem cells

Kawabata K., Sakurai F., Koizumi N., Hayakawa T., Mizuguchi H.
Mol. Pharmaceutics
3
95-103
2006

Efficient gene transfer into differentiated human trophoblast cells with adenovirus vector containing RGD motif in the fiber protein

Koizumi N., Mizuguchi H., Kondoh M., Fujii M., Nakanishi T., Utoguchi N., Watanabe Y.
Biol. Pharm. Bull.
29
1297-1299
2006

In vivo imaging of lymph node metastasis with telomerase-specific replication-selective adenovirus

Kishimoto H., Kojima T., Watanabe Y., Kagawa S., Fujiwara T., Uno F., Teraishi F., Kyo S., Mizuguchi H., Hashimoto Y., Urata Y., Tanaka N., Fujiwara T.
Nature Med.
12
1213-1219
2006

Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity

Uno K., Katagiri H., Yamada T., Ishigaki Y., Ogihara T., Imai J., Hasegawa Y., Gao J., Kaneko K., Iwasaki H., Ishihara H., Sasano H., Inukai K., Mizuguchi H., Asano T., Shiota M., Nakazato M., Oka Y.
Science
312
1656-1659
2006

Regulation of IL-27p28 gene by lipopolysacchraide in dendritic DC24 cells

Kamakura M., Morisawa K., Komi H., Tomatani A., Saito F., Konishi Y., Jin Y., Manabe T., Kuroda M., Imai S., Mizuguchi H., Taniguchi T.
Biochem. Biophys. Res. Commun.
349
1372-1377
2006

Characteristics of transcription-regulatory elements for gene expression from plasmid vectors in human trophoblast cell lines

Komiya E., Kondoh M., Mizuguchi H., Fujii M., Utoguchi N., Nakanishi T., Watanabe Y.
Placenta
27
934-938
2006

Impact of convective flow on the cellular uptake and transfection activity of lipoplex and adenovirus

Fujiwara T., Akita H., Furukawa K., Ushida T., Mizuguchi H., Harashima H.
Biol. Pharm. Bull.
29
1511-1515
2006

Dendritic cells modified to express fractalkine/CX3CL1 in the treatment of preexisting tumors

Nukiwa M., Andarini S., Zaini J., Xin H., Kanehira M., Suzuki T., Fukuhara T., Mizuguchi H., Hayakawa T., Saijo Y., Nukiwa T., Kikuchi T.
Eur. J. Immunol.
109
1019-1027
2006

Centrifugation enhances integrin-mediated transduction of dendritic cells by conventional and RGD-modified adenoviral vectors

Harui A., Roth MD., Sanghvi M., Vira D., Mizuguchi H., Basak SK.
J. Immunol. Methods
312
94-104
2006

Adenoviral-encoded antigens are presented by a subset of dendritic cells expressing alpha-v/beta-3 integrins

Harui A., Roth MD., Vira D., Sanghvi M., Mizuguchi H., Basak SK.
J. Leukocyte. Biol.
79
1271-1278
2006

Design and synthesis of a Tat-related gene transporter: a tool for carrying the adenovirus vector into cells

Kida S., Maeda M., Hojo K., Eto Y., Gao J.Q., Kurachi S., Mizuguchi H., Hayakawa T., Mayumi T., Nakagawa S., Kawasaki K.
Bioorg. Med. Chem. Lett.
16
743-735
2006

Quantitative comparison of intracellular trafficking and nuclear transcription between adenoviral and lipoplex systems

Hama S., Akita H., Ito R., Mizuguchi H., Hayakawa T., Harashima H.
Mol. Ther.
13
786-794
2006

Preparation of a claudin-targeting molecule using a C-terminal fragment of Clostridium perfringens enterotoxin

Ebihara C., Kondoh M., Hasuike N., Harada M., Mizuguchi H., Horiguchi Y., Fujii M., Watanabe Y.
J. Pharmacol. Exp. Ther.
316
255-260
2006

Tumor suppressive efficacy through augmentation of tumor-infiltrating immune cells by intratumoral injection of chemokine-expressing adenoviral vector

Okada N., Sasaki A., Niwa M., Okada Y., Hatanaka Y., Tani Y., Mizuguchi H., Nakagawa S., Fujita T., Yamamoto A.
Cancer Gene Ther.
13
393-405
2006

Gene expression of tumor cells both in vitro and in vivo enhanced by integrin-targeting adenovirus

Gao J-Q., Chen H-L., Nakagawa S., Mizuguchi H., Liang W-Q.
Acta Pharmaceutica Sinica
41
1116-1120
2006

Recent Advance of Development of Viral and Non-viral Vectors for Gene Therapy

Mizuguchi H.
Yakugaku Zasshi
126
1011
2006

Characterization of adenovirus serotype 35 vectors using genetically modified animals and nonhuman primates

Sakurai F., Kawabata K., Mizuguchi H.
Yakugaku Zasshi
126
1013-1019
2006

Development of non-viral vector based on the quantitative comparison of intracellular trafficking with viral vector

Akita H., Hama S., Mizuguchi H., Harashima H.
Yakugaku Zasshi
126
1047-1057
2006

新しいアデノウイルスベクターの開発

櫻井文教, 水口裕之
バイオサイエンスとインダストリー
64
11-16
2006

 大阪大学大学院 薬学研究科 分子生物学分野 

〒565-0871 大阪府吹田市山田丘1-6 大阪大学 大学院薬学研究科・薬学部 1号館 4階

TEL: 06-6879-8185 FAX: 06-6879-8187

 

Copyright© Laboratory of Biochemistry and Molecular Biology, Graduate School and School of Pharmaceutical Sciences, Osaka University

directed by Prof. Hiroyuki Mizuguchi

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