業績|論文・出版物|

2004

Targeted adenovirus vectors

Mizuguchi H., Hayakawa T.
Hum. Gene Ther.
15
1034-1044
2004

Adenovirus vector-mediated doxycycline-inducible RNA interference

Hosono T., Mizuguchi H., Katayama K., Xu ZL., Sakurai F., Ishii-Watabe A., Kawabata K., Yamaguchi T., Nakagawa S., Mayumi T., Hayakawa T.
Hum. Gene Ther.
15
813-819
2004

Efficient gene transfer into human trophoblast cells with adenovirus vector containing chimeric type 5 and 35 fiber protein

Koizumi, N., Mizuguchi H., Kondoh, M., Fujii, M., Hayakawa, T., Watanabe, Y.
Biol. Pharm. Bull.
27
2046-2048
2004

An improved method for detection of replication-competent retrovirus in retrovirus vector products

Uchida E., Sato K., Iwata A., Ishii-Watabe A., Mizuguchi H., Hikata M., Murata M., Yamaguchi T., Hayakawa T.
Biologicals
32
139-146
2004

High gene expression of the mutant adenovirus vector, both in vitro and in vivo, with the insertion of integrin-targeting peptide into the fiber

Gao J-Q., Inoue S., Tsukada Y., Katayama K., Eto Y., Kurachi S., Mizuguchi H., Hayakawa T., Tsutsumi Y., Mayumi T., Nakagawa S.
Pharmazie
59
571-572
2004

Simultaneous imaging of initiator/effector caspase activity and mitochondrial membrane potential during cell death in living HeLa cells

Kawai H., Suzuki T., Kobayashi T., Mizuguchi H., Hayakawa T., Kawanishi T.
Biochim. Biophys. Acta
1693
101-110
2004

Neutralizing antibody evasion ability of adenovirus vector induced by the bioconjugation of methoxypolyethylene glycol succinimidyl propionate (MPEG-SPA)

Eto Y., Gao J-Q., Sekiguchi F., Kurachi S., Katayama K., Mizuguchi H., Hayakawa T., Tsutsumi Y., Mayumi T., Nakagawa S.
Biol. Pharm. Bull.
27
936-938
2004

Antibody-targeted cell fusion

Nakamura T., Peng K-W., Vongpunsawad S., Harvey M., Mizuguchi H., Hayakawa T., Cattaneo R., Russell S.J.
Nat. Biotech.
22
331-336
2004

Optimization of antitumor efficacy and safety of in vivo cytokine gene therapy using RGD fiber-mutant adenovirus vector for preexisting murine melanoma

Okada Y., Okada N., Mizuguchi H., Takahashi K., Hayakawa T., Mayumi T., Mizuno N.
Biochim. Biophys. Acta
1670
172-180
2004

Anti-tumor activity of chemokine is affected by both kinds of tumors and the activation state of the host's immune system: implications for chemokine-based cancer immunotherapy

Okada N., Gao J-Q., Sasaki A., Niwa M., Okada Y., Nakayama T., Yoshie O., Mizuguchi H., Hayakawa T., Fujita T., Yamamoto A., Tsutsumi Y., Mayumi T., Nakagawa S.
Biochem. Biophys. Res. Commun.
317
68-76
2004

Overexpression of constitutively activated glutamate dehydrogenase induces insulin secretion through enhanced glutamate oxidation

Anno T., Uehara S., Katagiri H., Ohta Y., Ueda K., Mizuguchi H., Moriyama Y., Oka Y., Tanizawa Y.
Am. J. Physiol.
286
E280-285
2004

Tumor-suppressive activities by chemokines introduced into OV-HM cells using fiber-mutant adenovirus vectors

Gao J-Q, Alexandre L.S., Tsuda Y., Katayama K., Eto Y., Sekiguchi F., Mizuguchi H., Hayakawa T., Nakayama T., Yoshie O., Tsutsumi Y., Mayumi T., Nakagawa S.
Pharmazie
59
238-239
2004

RNA interfering approach for clarifying PPARγ pathway using lentiviral vector expressing short hairpin RNA

Katayama K., Wada K., Miyoshi H., Ohashi K., Tachibana M., Furuki R., Mizuguchi H., Hayakawa T., Nakajima A., Kadowaki T., Tsutsumi Y., Nakagawa1 S., Kamisaki Y., Mayumi T.
FEBS Lett.
560
178-182
2004

Dominant negative mutant of c-Jun gene transfer: a novel therapeutic strategy for colorectal cancer

Suto R., Tominaga K., Mizuguchi H., Sasaki E., Higuchi K., Kim S., Iwao H., Arakawa T.
Gene Ther.
11
187-193
2004

アデノウイルスベクター

水口裕之, 早川堯夫
Mebio
21
8-16
2004

 大阪大学大学院 薬学研究科 分子生物学分野 

〒565-0871 大阪府吹田市山田丘1-6 大阪大学 大学院薬学研究科・薬学部 1号館 4階

TEL: 06-6879-8185 FAX: 06-6879-8187

 

Copyright© Laboratory of Biochemistry and Molecular Biology, Graduate School and School of Pharmaceutical Sciences, Osaka University

directed by Prof. Hiroyuki Mizuguchi

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