論文・出版物 - 2016

Nagamoto Y., Takayama K., Ohashi K., Okamoto R., Sakurai F., Tachibana M., Kawabata K., Mizuguchi H. Transplantation of a human iPSC-derived hepatocyte sheet increases survival in mice with acute liver failure. J. Hepatol., 64, 1068-1075 (2016) PubMed

 

Machitani M. #, Sakurai F. #, Wakabayashi K., Nakatani K., Shimizu K., Tachibana M., Mizuguchi H. NF-kB promotes leaky expression of adenovirus genes in a replication-incompetent adenovirus vector. Sci. Rep., 6, 19922 (2016) # These authors contributed equally to this work. PubMed

 

Sakurai F., Narii N., Tomita K., Togo S., Takahashi K., Machitani M., Tachibana M., Ouchi M., Katagiri N., Urata Y., Fujiwara T., Mizuguchi H. Efficient detection of human circulating tumor cells without significant production of false-positive cells by a novel conditionally replicating adenovirus. Mol.Ther.Methods.Clin.Dev., 3, 16001 (2016) PubMed

 

Machitani M. #, Sakurai F. #, Wakabayashi K., Tomita K., Tachibana M., Mizuguchi H. Dicer functions as an antiviral system against human adenoviruses via cleavage of adenovirus-encoded noncoding RNA. Sci. Rep., 6, 27598 (2016)  # These authors contributed equally to this work. PubMed

 

Takayama K. #, Mitani S. #, Nagamoto Y., Sakurai F., Tachibana M., Taniguchi Y., Sakaguchi K., Mizuguchi H. Laminin 411 and 511 promote the cholangiocyte differentiation of human induced pluripotent stem cells. Biochem. Biophys. Res. Commun., 474, 91-96 (2016) # These authors contributed equally to this work. PubMed

 

Negoro R. #, Takayama K. #, Nagamoto Y., Sakurai F., Tachibana M., Mizuguchi H. Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells. Biochem. Biophys. Res. Commun., 472, 631-636 (2016) # These authors contributed equally to this work. PubMed

 

Nakamori D. #, Takayama K. #, Nagamoto Y., Mitani S., Sakurai F., Tachibana M., Mizuguchi H. Hepatic maturation of human iPS cell-derived hepatocyte-like cells by ATF5, c/EBPα, and PROX1 transduction. Biochem. Biophys. Res. Commun., 469, 424-429 (2016) # These authors contributed equally to this work. PubMed

 

Tsuzuki S. #, Tachibana M. #, Hemmi M., Yamaguchi T., Shoji M., Sakurai F., Kobiyama K., Kawabata K., Ishii K.J., Akira S., Mizuguchi H. TANK-binding kinase 1-dependent or -independent signaling elicits the cell type-specific innate immune responses induced by the adenovirus vector. Int. Immunol., 28, 105-115 (2016) # These authors contributed equally to this work. PubMed

 

Kita A., Hino N., Higashi S., Hirota K., Narumi R., Adachi J., Takafuji K., Ishimoto K., Okada Y., Sakamoto K., Tomonaga T., Takashima S., Mizuguchi H., Doi T. Adenovirus vector-based incorporation of a photo-cross-linkable amino acid into proteins in human primary cells and cancerous cell lines. Sci. Rep., 6, 36946 (2016) PubMed

 

Yanagihara K., Liu Y., Kanie K., Takayama K., Kokunugi M., Hirata M., Fukuda T., Suga M., Nikawa H., Mizuguchi H., Kato R., Furue M.K. Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells. Stem Cells Dev. 25, 1884-1897 (2016) PubMed

 

Wan L., Yao X., Faiola F., Liu B., Zhang T., Tabata Y., Mizuguchi H., Nakagawa S., Gao J.Q, Zhao R.C. Coating with Spermine-Pullulan Polymer Enhances Adenoviral Transduction of Mesenchymal Stem Cells. Int. J. Nanomed., 11, 6763-6769 (2016) PubMed

 

Onishi T., Tazawa H., Hashimoto Y., Takeuchi M., Otani T., Nakamura S., Sakurai F., Mizuguchi H., Kishimoto H., Umeda Y., Shirakawa Y., Urata Y., Kagawa S., Fujiwara T. Tumor-specific delivery of biologics by a novel T-cell line HOZOT. Sci Rep., 6, 38060 (2016) PubMed

 

Okamoto M., Asamura A., Tanaka K., Soeda T., Watanabe K., Mizuguchi H., Ikeda T. Expression of HIF-1α ODD domain fused canine caspase 3 by EGFR promoter-driven adenovirus vector induces cytotoxicity in canine breast tumor cells under hypoxia. Vet. Res. Commun., 40, 131-139 (2016) PubMed

 

Takehara K., Tazawa H., Okada N., Hashimoto Y., Kikuchi S., Kuroda S., Kishimoto H., Shirakawa Y., Narii N., Mizuguchi H., Urata Y., Kagawa S., Fujiwara T. Targeted photodynamic virotherapy armed with a genetically encoded photosensitizer. Mol. Cancer Ther., 15, 199-208 (2016) PubMed

 

Hemmi M, Mizuguchi H. Adenoviral Vector Construction II: Bacterial Systems, Adenoviral Vectors for Gene Therapy, Second Edition, Elsevier, David Curiel (eds.), (2016) WebSite

 

水口裕之、高山和雄;ヒトiPS細胞から肝細胞への分化誘導と毒性評価系への応用、SCAS NEWS 2016-Ⅱ、株式会社住化分析センター、3-7 (2016) Website

 

水口裕之、高山和雄;ヒトiPS細胞を用いた薬剤評価のための肝細胞の作製、iPS細胞、技術情報協会、124-130 (2016)

 

水口裕之、高山和雄;薬物毒性評価、臨床薬学テキストシリーズ、中山書店、乾賢一監修、233-239 (2016)

 

町谷充洋、水口裕之;標的化アデノウイルスベクターの開発、遺伝子医学MOOK 30 今、着実に実り始めた遺伝子治療~最新研究と今後の展望、金田安史編集、63-73 (2016) Website

 

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directed by Prof. Hiroyuki Mizuguchi

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