業績｜論文・出版物｜2015年

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Ozawa T., Takayama K., Okamoto R., Negoro R., Sakurai F., Tachibana M., Kawabata K., Mizuguchi H. Generation of enterocyte-like cells from human induced pluripotent stem cells for drug absorption and metabolism studies in human small intestine. Sci. Rep., 5:16479, (2015) PubMed

 

Mori J., Kawabata A., Tang H., Tadagaki K., Mizuguchi H., Kuroda K., Mori Y.. Human Herpesvirus-6 U14 induces cell-cycle arrest in G2/M phase by associating with a cellular protein, EDD. PLoS One, 10, e0137420 (2015) PubMed

 

Koizumi N., Yamagishi Y., Hirai T., Fujii M., Mizuguchi H., Watanabe Y. Efficient Adenovirus gene transfer methods in human colonic Caco-2 epithelial cells using capric acid. Biol. Pharm. Bull., 38, 1240-1244 (2015) PubMed

 

Tashiro K., Hirata N., Okada A., Yamaguchi T., Takayama K., Mizuguchi H., Kawabata K. Expression of coxsackievirus and adenovirus receptor separates hematopoietic and cardiac progenitor cells in Flk1-expressing mesoderm. Stem Cells Transl. Med., 4, 424-436 (2015) PubMed

 

Terasawa Y., Hotani T., Katayama Y., Tachibana M., Mizuguchi H., Sakurai F. Activity levels of cathepsins B and L in tumor cells are a biomarker for efficacy of reovirus-mediated tumor cell killing. Cancer Gene Ther., 22, 188-97 (2015) PubMed

 

Wakabayashi K., Machitani M., Shimizu K., Tachibana M., Sakurai F., Mizuguchi H. Quantitative analysis of virus-associated RNAI expression following transduction with a replication-incompetent adenovirus vector in vitro and in vivo. J. Mol. Genet. Med., 9:169 (2015) WebSite

 

Minami H., Tashiro K., Okada A., Hirata N., Yamaguchi T., Takayama K., Mizuguchi H., Kawabata K. Generation of brain microvascular endothelial-like cells from human induced pluripotent stem cells by co-culture with C6 glioma cells. PLOS ONE, 10, e0128890 (2015) PubMed

 

Iizuka S., Sakurai F., Shimizu K., Ohashi K., Nakamura S-I., Tachibana M., Mizuguchi H. Evaluation of transduction properties of an adenovirus vector in neonatal mice. BioMed Res.Int., Article ID 685374 (2015) PubMed

 

Hotani T., Tachibana M., Mizuguchi H., Sakurai F. Reovirus double-stranded RNA genomes and polyI:C induce down-regulation of hypoxia-inducible factor-alpha. Biochem. Biophys. Res. Commun., 460, 1041-1046 (2015) PubMed

 

Nagamoto Y., Takayama K., Tashiro K., Tateno C., Sakurai F., Tachibana M., Kawabata K., Ikeda K., Tanaka Y., Mizuguchi H. Efficient engraftment of human iPS cell-derived hepatocyte-like cells in uPA/SCID mice by overexpression of FNK, a Bcl-xLmutant gene. Cell Transplant., 24, 1127-1138 (2015) PubMed

 

Katayama Y., Terasawa Y., Tachibana M., Mizuguchi H., Sakurai F. Proteolytic disassembly of viral outer capsid proteins is crucial for reovirus-mediated type-I interferon induction in both reovirus-susceptible and reovirus-refractory tumor cells. BioMed Res.Int., Article ID 468457 (2015) PubMed

 

水口裕之；ヒトiPS細胞から肝細胞への高効率分化誘導法の開発とその実用化に関する研究、バイオサイエンスとインダストリー、73, 104-109 (2015)

 

高山和雄、水口裕之；ヒトiPS細胞由来肝細胞の創薬研究・非臨床試験への応用を目指して、薬剤学、75, 369-373(2015) J-STAGE

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