論文・出版物 - 2009

Matsui H., Sakurai F., Kurachi S., Tashiro K., Sugio K., Kawabata K., Yamanishi K., Mizuguchi H. Development of fiber-substituted adenovirus vectors containing foreign peptides in the adenovirus serotype 35 fiber knob. Gene Ther., 16, 1050-1057 (2009) PubMed

 

Tashiro K., Inamura M., Kawabata K., Sakurai F., Yamanishi K., Hayakawa T., Mizuguchi H. Efficient adipocyte and osteoblast differentiation from mouse induced pluripotent stem cells by adenoviral transduction. Stem Cells, 27, 102-1811 (2009) PubMed

 

Yao X., Yoshioka Y., Morishige T., Eto Y., Watanabe H., Okada Y., Mizuguchi H., Mukai Y., Okada N., Nakagawa S. Systemic administration of a PEGylated adenovirus vector with a cancer-specific promoter is effective in a mouse model of metastasis. Gene Ther., 16, 1395-404 (2009) PubMed

Kojima T., Hashimoto Y., Watanabe Y., Kagawa S., Uno F., Kuroda S., Tazawa H., Kyo S., Mizuguchi H., Urata Y., Tanaka N., Fujiwara T. A simple biological imaging system for detecting viable human circulating tumor cells. J. Clin. Invest., 119(10):3172-3181 (2009) PubMed

 

Xin H., Sun R., Kanehira M., Takahata T., Itoh J., Mizuguchi H., Saijo Y. Intratracheal delivery of CX3CL1-expressing mesenchymal stem cells to multiple lung tumors. Mol. Med., 15, 321-327 (2009) PubMed

 

Terao S., Acharya B., Suzuki T., Aoi T., Naoe M., Hamada K., Mizuguchi H., Gotoh A. Improved gene transfer into renal carcinoma cells using adenovirus vector containing RGD motif. Anticancer Res., 29, 2997-3001 (2009) PubMed

 

Eto Y., Yoshioka Y., Asavatanabodee R., Kida S., Maeda M., Mukai Y., Mizuguchi H., Kawasaki K., Okada N., Nakagawa S. Transduction of adenovirus vectors modified with cell penetrating peptides. Peptides, 30, 1548-1552 (2009) PubMed

Van Geer M.A., Bakker C.T., Koizumi N., Mizuguchi H., Wesseling J.G., Oude Elferink R.P.J., Bosma P.J., Ephrin A2 receptor targeting does not increase adenoviral pancreatic cancer transduction in vivo. World J. Gastroenterol., 15, 2754-2762 (2009) PubMed

Kurihara Y., Watanabe Y., Onimatsu H., Kojima T., Shirota T., Hatori M., Liu D., Kyo S., Mizuguchi H., Urata Y., Shintani S., Fujiwara T. Telomerase-Specific Virotheranostics for Human Head and Neck Cancer. Clin. Cancer Res., 15, 2335-2343 (2009) PubMed

 

Sakurai F., Nakamura S-I., Akitomo K., Shibata H., Terao K., Kawabata K., Hayakawa T., Mizuguchi H. Adenovirus serotype 35 vector-mediated transduction following direct administration into organs of nonhuman primates. Gene Ther., 16, 297-302 (2009) PubMed

 

Tashiro K., Kondo A., Kawabata K., Sakurai H., Sakurai F., Yamanishi K., Hayakawa T., Mizuguchi H. Efficient osteoblast differentiation from mouse bone marrow stromal cells with polylysin-modified adenovirus vectors. Biochem. Biophys. Res. Commun., 379, 127-132 (2009) PubMed

 

Ura T., Yoshida A., Xin K-Q., Yoshizaki S., Yashima S., Abe S, Mizuguchi H. Okuda K. Designed recombinant adenovirus type 5 vector induced env-specific CD8+ cytotoxic T lymphocytes and cross-reactive neutralizing antibodies against human immunodeficiency virus type 1. J. Gene Med., 11, 139-149 (2009) PubMed

 

Abe S., Okuda K., Ura T., Kondo A., Yoshida A., Yoshizaki S., Mizuguchi H., Klinman D., Shimada M. Adenovirus type 5 with modified hexons induces robust transgene-specific immune responses in mice with pre-existing immunity against adenovirus type 5. J. Gene Med., 11, 570-579 (2009) PubMed

Huang H., Sakurai F., Higuchi Y., Kawakami S., Hashida M., Kawabata K., Hayakawa T., Mizuguchi H. Suppressive effects of sugar-modified cationic liposome/NF-κB decoy complexes on adenovirus vector-induced innate immune responses. J. Control. Rel., 133, 139-145 (2009) PubMed

 

Gao J-Q., Tsuda Y., Han M., Xu D-H., Kanagawa N., Hatanaka Y., Tani Y., Mizuguchi H., Tsutsumi Y., Mayumi T., Okada N., Nakagawa S. NK cells are migrated and indispensable in the anti-tumor activity induced by CCL27 gene therapy. Cancer Immunol. Immunother., 58, 291-299 (2009) PubMed

 

Shimada M, Wang H-B., Ino A., Xu X-P., Yoshida A., Shinoda K., Ura T., Mizuguchi H., Klinman D., Luo J-L., Bai H., Okuda K. Effect of therapeutic immunization using Ad5/35 and MVA vectors on SIV-infection of rhesus monkeys undergoing anti-retroviral therapy. Gene Ther., 16, 218-228 (2009) PubMed

 

水口裕之;改良型アデノウイルスベクター開発の最前線、脳21、金芳堂、12(1)、123-131 (2009) WebSite

 

水口裕之;アデノウイルスベクターの作製・増幅・精製法、脳21、金芳堂、12(2)、246-251 (2009) WebSite

 

古江-楠田美保、山田弘、水口裕之;iPS細胞を活用した安全性・有効性評価系の構築、iPS細胞の産業的応用技術、シーエムシー出版、pp218~224 WebSite

 

水口裕之、櫻井文教、川端健二;アデノウイルスベクターのDDS、Pharm Tech Japan、25、2618-2624 (2009)

水口裕之;ゲノム解析と遺伝子DDSの設計・評価、Pharm Tech Japan、25(13) (2009) WebSite

 

水口裕之;組換えウイルスキャリア-遺伝子治療・ワクチン応用への新展開-、DDS、24(6)、569 (2009)

 

櫻井文教、川端健二、水口裕之;遺伝子組換えウイルスの安全性向上に向けた遺伝子改変~microRNAによる遺伝子発現制御システムを搭載した組換えウイルスの開発~、DDS、24(6)、572-581 (2009)

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directed by Prof. Hiroyuki Mizuguchi

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