業績|論文・出版物|2008年
Suzuki T., Sakurai F., Nakamura S-I., Kouyama E., Kawabata K., kondoh M., Yagi K., Mizuguchi H. miR-122a-regulated expression of a suicide gene prevents hepatotoxicity without altering antitumor effects in suicide gene therapy. Mol. Ther., 16, 1719-1726 (2008) PubMed
Sakurai H., Tashiro K., Kawabata K., Yamaguchi T., Sakurai F., Nakagawa S., Mizuguchi H. Adenoviral expression of suppressor of cytokine signaling-1 reduces adenovirus vector-induced innate immune response. J. Immunol., 180, 4931-4938 (2008) PubMed
Sakurai F., Nakamura S-I., Akitomo K., Shibata H., Terao K., Kawabata K., Hayakawa T., Mizuguchi H. Transduction properties of adenovirus serotype 35 vectors after intravenous administration into nonhuman primates. Mol. Ther., 16, 726-733 (2008) PubMed
Tashiro K., Kawabata K., Sakurai H., Kurachi S., Sakurai F., Yamanishi K., Mizuguchi H. Efficient adenovirus vector-mediated PPAR gamma gene transfer into mouse embryoid bodies promotes adipocyte differentiation, J. Gene Med., 10, 498-507 (2008) PubMed
Nakashima K., Sakurai F., Kawabata K., Mizuguchi H. Efficient gene delivery in human and rodent mast cells using adenovirus vectors. J. Control. Rel., 129, 215-222 (2008) PubMed
Sakurai H., Kawabata K., Sakurai F., Nakagawa S., Mizuguchi H. Innate immune response induced by gene delivery vectors. Int. J. Pharm., 354, 9-15 (2008) PubMed
Kurachi S., Koizumi N., Tashiro K., Sakurai H., Sakurai F., Kawabata K., Nakagawa S., Mizuguchi H. Modification of pIX or hexon based on fiberless Ad vectors is not effective for targeted Ad vectors. J. Control. Rel., 127, 88-95 (2008) PubMed
Yoshikawa T., Niwa T., Okada N., Mizuguchi H., Nakagawa S. Engineering of highly immunogenic long-lived DC vaccines by antiapoptotic protein gene transfer to enhance cancer vaccine potency. Gene Ther., 15, 1321-1329 (2008) PubMed
Gao J-Q., Kanagawa N., Xu D-H., Han M., Sugita T., Hatanaka Y., Tani Y., Mizuguchi H., Tsutsumi Y., Mayumi T., Okada N., Nakagawa S. Combination of two fiber-mutant adenovirus vectors, one encoding the chemokine FKN and another encoding cytokine interleukin 12, elicits notably enhanced anti-tumor responses. Cancer Immunol. Immunother., 57, 1657-64 (2008) PubMed
Arita E., Kondoh M., Isoda K., Nishimori H., Yoshida T., Mizuguchi H., Yagi K. Evaluation of promoter strength in mouse and rat primary hepatocytes using adenovirus vectors. Eur. J. Pharm. Biopharm., 70, 1-6 (2008) PubMed
Takahashi A., Komiya E., Kakutani H., Yoshida T., Fujii M., Horiguchi Y., Mizuguchi H., Tsutsumi Y., Tsunoda S-I., Koizumi N., Isoda K., Yagi K., Watanabe Y., Kondoh M. Domain mapping of a claudin-4 modulator, the C-terminal region of C-terminal fragment of Clostridium perfringens enterotoxin, by site-directed mutagenesis. Biochem. Pharmacol., 75, 1639-1648 (2008) PubMed
Kanagawa N., Koretomo R., Murakami S., Sakurai F., Mizuguchi H., Nakagawa S., Fujita T., Yamamoto A., Okada N. Factors involved in the maturation of murine dendritic cells transduced with adenoviral vector variants. Virology, 374, 411-420 (2008) PubMed
Yoshioka Y., Asavatanabodee R., Eto Y., Watanabe H., Morishige T., Yao X., Kida S., Maeda M., Mukai Y., Mizuguchi H., Kawasaki K., Okada N., Nakagawa S. Tat conjugation of adenovirus vector broadens tropism and enhances transduction efficiency. Life Science, 83, 747-755 (2008) PubMed
Larochelle N., Deol J., Srivastava V., Allen C., Mizuguchi H., Karpati G., Holland P., Nalbantoglu J. Downregulation of CD46 during muscle differentiation: implications for gene transfer to human skeletal muscle using group B adenoviruses. Hum. Gene Ther., 19, 133-142 (2008) PubMed
Sakurai F. Development and evaluation of a novel gene delivery vehicle composed of adenovirus serotype 35. Biol. Pharm. Bull., 31, 1819-1825 (2008) PubMed
Sakurai F. Development of a replication-incompetent adenovirus vector derived from subgroup B adenovirus serotype 35. Yakugaku Zasshi, 128, 1751-1761 (2008) PubMed
衛藤佑介、吉岡靖雄、Asavatanabodee R、水口裕之、向洋平、岡田直貴、中川晋作;標的指向性を有するバイオコンジュゲート化アデノウイルスベクターの開発、薬学雑誌、128、1733-1742 (2008) J-STAGE
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