論文・出版物 - 2001

Mizuguchi H., Koizumi N., Hosono T., Utoguchi N., Watanabe Y., Kay MA., Hayakawa T. A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the HI loop of their fiber knob. Gene Ther., 8, 730-735 (2001) PubMed

 

Mizuguchi H., Kay MA., Hayakawa T. In vitro ligation-based cloning of foreign DNAs into the E3 and E1 deletion regions for generation of recombinant adenovirus vectors.  BioTechniques, 30, 1112-1114, 1116 (2001) PubMed

 

Mizuguchi H., Hayakawa T. Characteristics of adenovirus-mediated tetracycline-controllable expression system. Biochim. Biophys. Acta, 1568, 21-29 (2001) PubMed

 

Koizumi N., Mizuguchi H., Hosono T., Ishii-Watabe A., Uchida E., Utoguchi N., Watanabe Y., Hayakawa T. Efficient gene transfer by fiber-mutant adenoviral vectors containing RGD peptide. Biochim. Biophys. Acta, 1568, 13-20 (2001) PubMed

 

Xu ZL., Mizuguchi H., Ishii-Watabe A., Uchida E., Mayumi T., Hayakawa T. Optimization of transcriptional regulatory elements for constructing plasmid vectors. Gene, 272, 149-156 (2001) PubMed

 

Mizuguchi H., Kay M.A., Hayakawa T. Approaches for generating recombinant adenovirus vectors. Adv. Drug. Deli. Rev., 52, 165-176 (2001) PubMed

 

Maruyama K., Akiyama Y., Nara-Ashizawa N., Hojo T., Cheng JY., Mizuguchi H., Hayakawa T., Yamaguchi K. Adenovirus-mediated MUC1 gene transduction into human blood-derived dendritic cells. J. Immunother., 24, 345-353 (2001) PubMed

 

Okada N., Saito T., Masunaga Y., Tsukada Y., Nakagawa S., Mizuguchi H., Mori K., Okada Y., Fujita T., Hayakawa T., Mayumi T., Yamamoto A. Efficient antigen gene transduction using Arg-Gly-Asp fiber-mutant adenovirus vectors can potentiate antitumor vaccine efficacy and maturation of murine dendritic cells.  Cancer Res., 61, 7913-7919 (2001) PubMed

 

Okada N., Tsukada Y., Nakagawa S., Mizuguchi H., Mori K., Saito T., Fujita T., Yamamoto A., Hayakawa T., Mayumi T. Efficient gene delivery into dendritic cells by fiber-mutant adenovirus vectors. Biochem. Biophys. Res. Commun., 282, 173-179 (2001) PubMed

 

Ishii-Watabe A., Uchida E., Mizuguchi H., Hayakawa T. Involvement of a calcium-independent pathway in plasmin-induced platelet shape change.  Life Science, 69, 945-960 (2001) PubMed

 

Nagayama Y., Nishihara E., Namba H., Yokoi H., Hasegawa M., Mizuguchi H., Hayakawa T., Hamada H., Yamashita S., Niwa M. Targeting the replication of adenovirus to p53-defective thyroid carcinoma with a p53-regulated cre/loxP system. Cancer Gene Ther., 8, 36-44 (2001) PubMed

 

Nakanishi M., Akuta T., Nagoshi E., Eguchi A., Mizuguchi H., Senda T. Nuclear targeting of DNA. Eur. J. Pharm. Sci., 13, 17-24 (2001) PubMed

 

Sakurai F, Nishioka T, Yamashita F, Takakura Y, and Hashida M. Effects of erythrocytes and serum proteins on lung accumulation of lipoplexes containing cholesterol or DOPE as a helper lipid in the single-pass rat lung perfusion system. Eur. J. Pharm. Biopharm., 52, 165-172 (2001) PubMed

 

Sakurai F, Nishioka T, Saito H, Baba T, Okuda A, Matsumoto O, Taga T, Yamashita F, Takakura Y, and Hashida M. Interaction between DNA-cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: the role of the neutral helper lipid. Gene Ther., 8, 677-686 (2001) PubMed

 

Egawa T, Kawabata K, Kawamoto H, Amada K, Okamoto R, Fujii N, Kishimoto T, Katsura Y, Nagasawa T. The earliest stages of B cell development require a chemokine stromal cell-derived factor/pre-B cell growth-stimulating factor. Immunity, 15, 323-334 (2001) PubMed

 

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早川堯夫、水口裕之;遺伝子治療用医薬品の実用化と一層の進展に向けて-新世代アデノウイルスベクターの開発-、医薬ジャーナル、医薬ジャーナル社、37、101-107 (2001) WebSite

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directed by Prof. Hiroyuki Mizuguchi

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